Tisch
CA Syringe Filters w/ 3 Pre-Filters, 0.22 um, 25mm, Nonsterile, 100/Pk SKU: SF18292

Cellulose Acetate (CA) Syringe Filters w/ 3 Pre-Filters - SF18292

Pharmaceutical and biotechnology laboratories demand sterile-grade filtration for biological samples carrying heavy particulate burdens that overwhelm standard single-stage membranes during routine processing operations. Triple-layer prefiltration delivers extended operational capacity for challenging matrices. Advanced 0.22µm cellulose acetate membrane construction with validated 40.6psi bubble point and 4.08cm² filtration area provides bacterial retention while processing medium-volume samples where dirt load capacity determines filtration success.

Key Cellulose Acetate Membrane Characteristics

• 0.22µm pore size achieves bacterial retention and sterile-grade filtration performance for cell culture media, protein solutions, and biological samples requiring bioburden reduction
• Hydrophilic cellulose acetate surface processes aqueous samples immediately without pre-wetting protocols, eliminating methanol exposure risks and accelerating sample preparation throughput
• Low protein binding affinity maintains biomolecule concentrations throughout filtration, preventing adsorption losses that compromise analytical accuracy in protein-sensitive applications
• Validated 40.6psi bubble point ensures membrane integrity and consistent pore size distribution across production batches, supporting reproducible bacterial retention in quality-critical workflows
• Broad aqueous buffer compatibility supports biological and pharmaceutical applications without membrane degradation, though aggressive organic solvents require alternative membrane chemistries

Key Construction Characteristics

• Triple prefilter configuration with two glass fiber layers plus polypropylene stage captures gross particulates upstream of the membrane, dramatically extending operational life when samples carry heavy debris loads
• 400µL holdup volume balances sample recovery with filtration capacity in medium-volume applications, preserving material while accommodating the triple prefilter system's additional internal volume
• Durable polypropylene housing withstands operating pressures to 87psi and temperatures to 60°C, supporting diverse processing conditions across manual and vacuum-assisted filtration configurations
• Luer-Lok and Luer Slip connections provide universal syringe compatibility, integrating seamlessly into existing laboratory workflows without requiring specialized adapters or connection modifications

When your laboratory processes particulate-rich biological samples requiring sterile-grade filtration, single-stage membranes clog rapidly and force costly filter replacements. The 25mm platform with triple prefilter protection and 4.08cm² cellulose acetate membrane processes up to 50ml throughput per device. This configuration delivers the operational capacity your workflows demand, enabling you to complete sample batches without interruption while maintaining sterile filtration performance critical for biological and pharmaceutical applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40.6psi

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

32ml

Holdup Volume

400µl

Material

Cellulose Acetate (CA)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-170μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Nonsterile

Sterilization

Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophilic

• Cell Culture Media Sterilization - Removes bacteria and mycoplasma from culture media and serum supplements, ensuring sterile conditions for sensitive cell lines and tissue culture
• Biological Sample Clarification - Filters particulate-laden lysates and tissue homogenates before analysis, protecting downstream instrumentation while achieving bacterial retention
• Pharmaceutical Buffer Preparation - Sterilizes formulation buffers and reagent solutions for aseptic processing, meeting quality requirements for sterile pharmaceutical manufacturing
• Environmental Water Testing - Prepares turbid water samples for microbial analysis, removing gross particulates without compromising bacterial recovery for regulatory compliance testing
• Protein Solution Filtration - Clarifies antibody preparations with minimal adsorption loss, removing aggregates and bioburden before downstream purification or analytical procedures
• HPLC Sample Preparation - Protects analytical columns from particulate fouling in complex biological matrices, extending equipment life while maintaining sterile sample integrity