Tisch
CA Syringe Filters w/ 3 Pre-Filters, 0.22 um, 25mm, Sterile, 100/Pk SKU: SF18293

Cellulose Acetate (CA) Syringe Filters w/ 3 Pre-Filters - SF18293

Precision 0.22µm cellulose acetate membrane construction with validated 40.6psi bubble point and triple-layer glass fiber plus polypropylene prefiltration delivers sterile-grade bacterial retention in a gamma-sterilized, ready-to-use configuration. Cell culture and pharmaceutical applications benefit from immediate deployment without pre-sterilization steps. Combined with 4.08cm² filtration area and extended 50ml throughput capacity, this sterile platform handles particulate-rich biological samples where dirt load capacity and bacterial retention both matter for successful processing.

Key Cellulose Acetate Membrane Characteristics

• 0.22µm pore size provides bacterial retention and sterile-grade filtration for cell culture media, biological buffers, and pharmaceutical formulations requiring bioburden reduction
• Hydrophilic surface chemistry enables immediate aqueous sample processing without pre-wetting protocols, eliminating organic solvent exposure and streamlining sterile workflows
• Low protein binding properties preserve biomolecule concentrations during filtration, critical when protein recovery determines analytical success in sensitive biological applications
• Validated 40.6psi bubble point confirms membrane integrity and consistent pore size distribution, supporting reproducible bacterial retention performance across quality-sensitive sterile processing operations
• Temperature stability to 60°C accommodates warm sample filtration requirements while organic solvent limitations require consideration for non-aqueous applications

Key Construction Characteristics

• Triple prefilter system with dual glass fiber layers plus polypropylene stage captures gross particulates before membrane contact, dramatically extending operational life in turbid biological samples
• 400µL holdup volume balances recovery efficiency with filtration capacity in medium-volume applications, accommodating the triple prefilter configuration while preserving valuable sample material
• Gamma-sterilized construction provides ready-to-use sterile integrity straight from the package, eliminating pre-sterilization steps and reducing contamination risks in aseptic processing environments
• Luer-Lok and Luer Slip connections deliver universal compatibility with standard syringes and tubing, integrating seamlessly into sterile workflows without specialized adapters

Designed for your sterile processing workflows where particulate-rich samples challenge single-stage membranes, this gamma-sterilized platform eliminates pre-sterilization steps. Triple prefilter protection with 4.08cm² cellulose acetate membrane processes up to 50ml throughput per device. Combined with validated bacterial retention and low protein binding performance, this configuration provides your laboratory with the operational capacity to complete sterile filtration batches efficiently while maintaining the sample integrity and microbiological control essential for cell culture, pharmaceutical, and biological applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40.6psi

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

32ml

Holdup Volume

400µl

Material

Cellulose Acetate (CA)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-170μm

Pack Count

100

Pore Size (µm)

0.22

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Sterile

Volume Throughput (ml)

50ml

Weight

0.88

Wetability

Hydrophilic

• Cell Culture Media Sterilization - Removes bacteria from culture media and serum supplements immediately upon opening, ensuring sterile conditions for sensitive mammalian cell lines
• Biological Buffer Preparation - Sterilizes formulation buffers and reagent solutions for tissue culture and molecular biology applications requiring validated bacterial retention
• Pharmaceutical Sample Filtration - Filters protein therapeutics and drug formulations with minimal adsorption loss while achieving sterile-grade bioburden reduction for quality control testing
• Aseptic Processing Operations - Supports cleanroom workflows requiring sterile filtration of biological samples without introducing pre-sterilization delays into time-sensitive protocols
• Environmental Water Analysis - Prepares turbid water samples for microbial enumeration, removing interfering particulates while maintaining bacterial recovery for regulatory compliance testing
• Sterile Sampling Applications - Enables sterile collection of biological fluids and culture supernatants for downstream microbiological or analytical testing requiring contamination-free specimens