Tisch
CA Syringe Filters w/ 3 Pre-Filters, 0.45 um, 25mm, Nonsterile, 100/Pk SKU: SF18294

Cellulose Acetate (CA) Syringe Filters w/ 3 Pre-Filters - SF18294

Featuring 0.45µm cellulose acetate membrane technology with triple-layer glass fiber plus polypropylene prefiltration and validated 23.2psi bubble point, this medium-volume syringe filter delivers robust clarification capacity for particulate-laden biological samples. Exceptional 65ml flow rate accelerates sample processing when throughput drives laboratory productivity. Combined with 4.08cm² filtration area and extended 50ml operational capacity, this nonsterile platform handles turbid aqueous samples where dirt load challenges standard single-stage membranes.

Key Cellulose Acetate Membrane Characteristics

• 0.45µm pore size removes particulates and cellular debris from biological matrices, clarifying samples for downstream analysis without achieving sterile-grade bacterial retention
• Hydrophilic membrane surface processes aqueous solutions immediately upon contact, eliminating pre-wetting delays that slow workflow throughput in time-sensitive laboratory operations
• Low protein binding affinity maintains biomolecule concentrations throughout clarification, preserving sample integrity when protein recovery determines analytical accuracy in your applications
• Validated 23.2psi bubble point ensures consistent pore size distribution across production batches, supporting reproducible clarification performance in quality-sensitive workflows
• Broad aqueous buffer compatibility supports biological and environmental applications without membrane degradation, though organic solvent resistance remains limited compared to alternative membrane chemistries

Key Construction Characteristics

• Triple prefilter configuration with dual glass fiber layers plus polypropylene stage extends operational life dramatically, capturing gross particulates before they reach the cellulose acetate membrane
• 400µL holdup volume balances sample recovery with filtration capacity in medium-volume processing, accommodating the triple prefilter system while preserving valuable sample material
• Autoclavable polypropylene housing enables user sterilization at 121°C for 30 minutes before first use, supporting customized preparation protocols and reducing operational costs
• Luer-Lok and Luer Slip connections provide universal compatibility with standard laboratory syringes, integrating seamlessly into existing sample preparation workflows without specialized adapters

When your laboratory processes particulate-rich biological samples requiring efficient clarification, single-stage membranes clog quickly and interrupt workflow continuity. The 25mm platform with triple prefilter protection delivers 4.08cm² of cellulose acetate membrane area and exceptional 65ml flow rates. Combined with 50ml throughput capacity and autoclavable construction, this configuration provides your laboratory with the operational efficiency to complete clarification batches without interruption, maintaining the sample quality essential for accurate biological and environmental analysis.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

23.2psi

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

65ml

Holdup Volume

400µl

Material

Cellulose Acetate (CA)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-170μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Nonsterile

Sterilization

Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophilic

• Cell Culture Media Clarification - Removes cellular aggregates from conditioned media before analysis, preserving secreted proteins for downstream biomarker quantification
• Biological Sample Preparation - Clarifies lysates and tissue homogenates before spectrophotometric analysis, eliminating particulates that interfere with absorbance measurements
• Environmental Water Testing - Prepares turbid water samples for ion chromatography and microbial analysis, removing gross particulates without compromising analytical sensitivity
• HPLC Sample Protection - Guards analytical columns from particulate fouling in complex biological matrices, extending equipment life and maintaining chromatographic resolution
• Aqueous Buffer Filtration - Clarifies phosphate buffers and electrophoresis reagents for laboratory applications requiring particulate-free formulations
• Protein Solution Processing - Filters antibody preparations and enzyme solutions with minimal adsorption, removing aggregates before downstream purification or analytical procedures