Tisch
CA Syringe Filters w/ 3 Pre-Filters, 0.45 um, 25mm, Sterile, 100/Pk SKU: SF18295

Cellulose Acetate (CA) Syringe Filters w/ 3 Pre-Filters - SF18295

Particulate-rich biological samples requiring aseptic clarification create operational bottlenecks when single-stage membranes clog rapidly, forcing you to interrupt sterile workflows for filter replacement and compromise processing schedules. Triple-layer prefiltration extends operational capacity dramatically while maintaining sterile integrity. Gamma-sterilized 0.45µm cellulose acetate membrane construction with validated 23.2psi bubble point and exceptional 65ml flow rates delivers ready-to-use clarification where dirt load capacity determines processing success.

Key Cellulose Acetate Membrane Characteristics

• 0.45µm pore size removes cellular debris and particulates from biological samples, clarifying matrices for downstream analysis while providing particulate control in sterile processing environments
• Hydrophilic surface chemistry enables immediate aqueous sample processing straight from the sterile package, eliminating pre-wetting steps that introduce contamination risks in aseptic workflows
• Low protein binding properties preserve biomolecule concentrations during clarification, essential when your analytical sensitivity depends on maintaining accurate protein quantification throughout sample preparation
• Validated 23.2psi bubble point ensures consistent pore size distribution and reproducible clarification performance, supporting quality control requirements in regulated laboratory environments
• Aqueous buffer compatibility supports biological and pharmaceutical applications without membrane degradation, though aggressive organic solvents require alternative membrane chemistries

Key Construction Characteristics

• Triple prefilter system with dual glass fiber layers plus polypropylene protection captures gross particulates upstream of the membrane, dramatically extending operational life in turbid samples
• 400µL holdup volume balances sample recovery with filtration capacity in medium-volume applications, accommodating the triple prefilter configuration while preserving sample material in your workflows
• Gamma-sterilized construction provides ready-to-use sterile integrity immediately upon opening, eliminating pre-sterilization delays and reducing contamination risks in cleanroom processing environments
• Luer-Lok and Luer Slip connections deliver universal compatibility with sterile syringes and aseptic transfer equipment, integrating seamlessly into validated sterile workflows

Built to support your sterile processing workflows where particulate-rich samples challenge standard single-stage membranes, this gamma-sterilized platform eliminates pre-filtration bottlenecks. Triple prefilter protection with 4.08cm² cellulose acetate membrane delivers exceptional 65ml flow rates and 50ml throughput capacity per device. Combined with ready-to-use sterile integrity and low protein binding characteristics, this configuration ensures your laboratory can complete aseptic clarification batches efficiently while maintaining the sample quality and microbiological control essential for biological and pharmaceutical applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

23.2psi

Connection Type

Luer-Lok/ Luer Slip

Construction

PP

Diameter

25mm

Filtration Area

4.08cm²

Flow Rate

65ml

Holdup Volume

400µl

Material

Cellulose Acetate (CA)

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

80-170μm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

GF+GF+PP

Sterility

Sterile

Volume Throughput (ml)

50ml

Weight

0.88

Wetability

Hydrophilic

• Sterile Sample Clarification - Removes particulates from biological fluids in aseptic environments, maintaining sterile handling during clarification
• Cell Culture Media Processing - Clarifies conditioned media and supplements under sterile conditions, preserving integrity for downstream assays
• Pharmaceutical Sample Preparation - Filters turbid formulation samples with minimal protein adsorption, maintaining sterile processing requirements
• Cleanroom Operations - Supports aseptic workflows requiring particulate removal without introducing pre-sterilization steps in protocols
• Biological Buffer Clarification - Prepares sterile buffers and reagents for tissue culture applications requiring particulate removal and sterility
• Environmental Sample Processing - Clarifies turbid water samples for microbial analysis, removing particulates while maintaining aseptic protocols