Cellulose Acetate (CA) Syringe Filters - SF14487
Medium-volume pharmaceutical and biological workflows face persistent challenges maintaining bacterial retention while processing particulate-laden samples that rapidly overwhelm single-membrane filters, creating throughput bottlenecks in sterile processing operations. Traditional sterile filtration lacks the dirt-load capacity to sustain flow rates through challenging matrices, compromising operational efficiency. Integrated polypropylene prefiltration combined with 0.22µm cellulose acetate membrane technology resolves these limitations through multi-stage design that protects the sterile membrane from premature fouling. Technical specifications include validated 40.6psi bubble point ensuring bacterial retention, 25mm platform with 4.08cm² filtration area, and autoclavable construction supporting 32ml flow rate with 50ml throughput capacity for demanding sterile processing of moderately dirty samples.
Key Cellulose Acetate Membrane Characteristics
- Sterile-grade 0.22µm retention provides validated bacterial removal for pharmaceutical and biological applications where absolute contamination control throughout sample processing remains non-negotiable
- Integrated polypropylene prefilter captures gross particulates upstream of the cellulose acetate membrane, extending filter life and maintaining consistent flow rates through dirty samples
- Hydrophilic membrane platform enables immediate aqueous sample processing without pre-wetting steps, eliminating preparation delays and accelerating operational throughput
- Selective chemical compatibility maintains stable operation with water-based solutions and buffers while incompatible with acids, ketones, dichloromethane, and sodium hydroxide
- Autoclavable construction allows users to sterilize filters in-house at 121°C for 30 minutes, supporting customized preparation protocols and reducing inventory complexity
Key Construction Characteristics
- Moderate 100µL holdup volume accommodates prefiltration design while supporting 10-100ml processing where throughput capacity justifies slightly increased sample retention
- Generous 4.08cm² filtration area enables sustained 32ml flow rate performance at 87psi maximum operating pressure for medium-volume sterile filtration applications
- Universal Luer-Lok/Luer Slip interface ensures compatibility with standard laboratory syringes, eliminating adapter requirements and streamlining workflow integration
- Thermally stable polypropylene housing maintains reliable structural integrity up to 60°C maximum temperature for ambient and moderately elevated processing conditions
Built to support your sterile processing requirements where particulate loading compromises standard filters, multi-stage prefiltration technology delivers operational excellence. Validated 40.6psi bubble point ensures bacterial retention confidence throughout pharmaceutical workflows. Autoclavable construction combined with moderate holdup design supports your laboratory operations requiring economical yet dependable sterile filtration of moderately dirty sample matrices.
For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 40.6psi
- Burst Pressure (psi)
- 87psi.
- Connection Type
- Luer-Lok/ Luer Slip
- Construction
- PP
- Diameter
- 25mm
- Filtration Area
- 4.08cm²
- Flow Rate
- 32ml
- Holdup Volume
- 100µl
- Incompatibility
- Acids, dichloromethane, sodium hydroxide, ketones
- Material
- Cellulose Acetate (CA)
- Maximum Operating Pressure
- 87psi
- Maximum Operating Temperature (°C)
- 60°C
- Membrane Thickness (µm)
- 80-170μm
- Pack Count
- 100
- Pore Size (µm)
- 0.22
- Prefilter (Yes/No)
- Yes
- Prefilter Material
- PP
- Sterility
- Nonsterile
- Sterilization
- Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours
- Volume Throughput (ml)
- 50ml
- Weight
- 0.52
- Wetability
- Hydrophilic
- Dirty Sample Sterilization - Prefiltration handles particulate-laden biological matrices while maintaining validated bacterial retention capabilities
- Fermentation Broth Processing - Multi-stage design filters cell culture fluids with biomass loading before downstream sterile operations
- Pharmaceutical Quality Control - Processes manufacturing samples requiring bacterial removal despite moderate particulate content in routine workflows
- Serum and Plasma Filtration - Extended capacity handles viscous biological samples while autoclavable construction supports sterilization requirements
- Aqueous Reagent Sterilization - Hydrophilic membrane filters water-based laboratory solutions without pre-wetting preparation steps
- Biological Extract Clarification - Prefilter protects sterile membrane from fouling during processing of crude tissue culture preparations