Tisch
MCE Syringe Filter, 0.45um, 20mm, Double Luer-Lok, Nonsterile, 100Pk SKU: SPEC18178

Mixed Cellulose Ester (MCE) Syringe Filter - SPEC18177

Sterilization workflows often face the challenge of protein loss through membrane adsorption, reducing biomolecule recovery and compromising analytical results in critical applications. The SPEC18177 addresses this issue with a 0.22 µm mixed cellulose ester membrane that removes bacteria while maintaining naturally low protein binding characteristics essential for preserving sample integrity. Your operations benefit from cellulosic chemistry that provides effective bacterial removal without the protein adsorption problems common to synthetic membranes, while the 20mm configuration with threaded double Luer Lock connections ensures secure attachment during cell culture media sterilization, biological buffer filtration, protein solution processing, HPLC mobile phase preparation, pharmaceutical quality control, and microbiological testing applications.

Key Membrane Characteristics

• 0.22 µm mixed cellulose ester membrane delivers sterile-grade filtration with naturally low protein binding for biomolecule preservation
• 3.1 cm² filtration area in the 20mm diameter configuration provides appropriate processing capacity for routine laboratory sterilization applications
• 29 psi bubble point ensures membrane integrity while confirming effective bacterial retention during filtration operations
• Hydrophilic cellulosic structure enables immediate aqueous sample processing while minimizing protein adsorption for recovery
• Low extractables profile maintains solution purity during filtration of sensitive biological samples and pharmaceutical preparations

Key Construction Characteristics

• Durable acrylonitrile butadiene styrene housing withstands operating pressures up to 72.5 psi with burst protection rated to 116 psi
• Threaded double Luer Lock inlet and outlet connections provide secure, leak-free attachment during sterilization operations
• Autoclavable construction supports your in-house sterilization protocols when preparing filters for aseptic processing applications
• Nonsterile configuration offers flexibility where you can sterilize filters before use or employ them for non-biological sample preparation

Your sterilization operations gain reliability from the mixed cellulose ester composition that naturally resists protein adsorption during bacterial removal. The 3.1 cm² filtration area handles routine laboratory sample volumes appropriately while the 0.22 µm pore size provides effective bacterial retention. Threaded double Luer Lock connections maintain secure attachment during critical sterilization operations while autoclavable construction and hydrophilic membrane chemistry support diverse applications across pharmaceutical, biotechnology, and microbiological testing laboratories.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer-Lok

Construction

Acrylonitrile Butadiene Styrene (ABS)

Diameter

20mm

Dimensions

23mmx25.2mm

Filtration Area

3.1cm²

Material

Mixed Cellulose Ester (MCE)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

60°C

Pack Count

100

Pore Size (µm)

0.45

Sterility

Nonsterile

Weight

0.60

Wetability

Hydrophilic

• Cell Culture Media Sterilization - Remove bacteria from nutrient solutions while maintaining protein and growth factor integrity for mammalian cell lines
• Biological Buffer Filtration - Sterilize phosphate buffers and reagent solutions before use in enzyme assays or protein purification workflows
• Protein Solution Processing - Filter antibody preparations and enzyme solutions while preserving concentration through low-binding membrane chemistry
• HPLC Mobile Phase Prep - Sterilize aqueous solvent mixtures to remove bacteria and particulates before chromatographic analysis
• Pharmaceutical QC Testing - Remove bacteria from drug formulations and excipient solutions before sterility testing or analytical measurements
• Microbiological Testing - Sterilize dilution blanks and culture media components before enumeration procedures in quality control programs