Tisch
MCE Syringe Filter, 0.45um, 20mm, Double Luer-Lok, Nonsterile, 100Pk SKU: SPEC18178

Mixed Cellulose Ester (MCE) Syringe Filter - SPEC18178

Clarification workflows often face the challenge of protein loss through membrane adsorption, reducing biomolecule recovery and compromising analytical results in critical applications. The SPEC18178 addresses this issue with a 0.45 µm mixed cellulose ester membrane that removes particulates while maintaining naturally low protein binding characteristics. Your operations benefit from cellulosic chemistry that provides effective clarification without the protein adsorption problems common to synthetic membranes. The 20mm configuration features threaded double Luer Lock connections to ensure secure attachment during routine tasks. Such design supports cell culture media clarification, biological buffer filtration, and protein solution processing.

Key Membrane Characteristics

• 0.45 µm mixed cellulose ester membrane delivers efficient clarification with naturally low protein binding for biomolecule preservation
• 3.1 cm² filtration area in the 20mm diameter configuration provides appropriate processing capacity for routine laboratory clarification applications
• 29 psi bubble point ensures membrane integrity while confirming effective particulate retention during filtration operations
• Hydrophilic cellulosic structure enables immediate aqueous sample processing while minimizing protein adsorption for recovery
• Low extractables profile maintains solution purity during filtration of sensitive biological samples and pharmaceutical preparations

Key Construction Characteristics

• Durable acrylonitrile butadiene styrene housing withstands operating pressures up to 72.5 psi with burst protection rated to 116 psi
• Threaded double Luer Lock inlet and outlet connections provide secure, leak-free attachment during filtration operations
• Autoclavable construction supports your in-house sterilization protocols when preparing filters for aseptic processing applications
• Nonsterile configuration offers flexibility where you can sterilize filters before use or employ them for non-biological sample preparation

Your clarification operations gain reliability from the mixed cellulose ester composition that naturally resists protein adsorption during particulate removal. The 3.1 cm² filtration area handles routine laboratory sample volumes appropriately, while the 0.45 µm pore size provides effective retention of fine precipitates. Threaded double Luer Lock connections maintain secure attachment during critical filtration operations. Furthermore, the autoclavable construction and hydrophilic membrane chemistry support diverse applications across pharmaceutical, biotechnology, and analytical testing laboratories. You can depend on this robust design to deliver consistent clarified filtrates for your most sensitive biological research projects.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Construction

Acrylonitrile Butadiene Styrene (ABS)

Diameter

20mm

Dimensions

23mmx25.2mm

Filtration Area

3.1cm²

Material

Mixed Cellulose Ester (MCE)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

60°C

Pack Count

100

Pore Size (µm)

0.45

Sterility

Nonsterile

Weight

0.60

Wetability

Hydrophilic

• Cell Culture Media Clarification – Remove particulates from nutrient solutions while maintaining protein and growth factor integrity for cell lines
• Biological Buffer Filtration – Clarify phosphate buffers and reagent solutions before use in enzyme assays or protein purification workflows
• Protein Solution Processing – Filter antibody preparations and enzyme solutions while preserving concentration through low-binding membrane chemistry
• HPLC Mobile Phase Prep – Filter aqueous solvent mixtures to remove particulates and precipitates before chromatographic analysis to protect columns
• Pharmaceutical QC Testing – Remove particulates from drug formulations and excipient solutions before analytical measurements
• Microbiological Media Clarification – Clarify dilution blanks and culture media components before use in quality control programs