Tisch
MCE Syringe Filter, 0.45um, 20mm, Double Luer-Lok, Sterile, 100/Pk SKU: SPEC18183

Mixed Cellulose Ester (MCE) Syringe Filter - SPEC18183

The SPEC18183 combines a 0.45 µm mixed cellulose ester membrane with a 3.1 cm² filtration area and a 29 psi bubble point, engineered for the clarification of biological samples that require biomolecule preservation. This hydrophilic cellulosic membrane removes particulates while maintaining naturally low protein binding characteristics that prevent sample loss during processing. Your sterile-ready laboratory operations span cell culture media clarification where serum supplements and growth factors require particulate removal, biological buffer filtration before enzyme assays, protein solution processing preserving antibody concentrations, HPLC sample preparation protecting chromatography columns, pharmaceutical quality control requiring analytical precision, and microbiological media clarification where complex components demand particulate-free conditions while maintaining solution integrity throughout processing workflows.

Key Membrane Characteristics

• 0.45 µm mixed cellulose ester membrane provides clarification with naturally low protein binding for biomolecule preservation
• 3.1 cm² filtration area in the 20mm diameter configuration handles routine laboratory sample volumes efficiently
• 29 psi bubble point ensures membrane integrity while the hydrophilic cellulosic structure enables immediate aqueous sample processing
• Low extractables profile maintains solution purity during filtration of sensitive biological samples and pharmaceutical preparations
• Broad chemical compatibility supports aqueous buffers, alcohols, and mild organic solvents across diverse laboratory applications

Key Construction Characteristics

• Durable housing withstands operating pressures up to 72.5 psi with burst protection rated to 116 psi
• Double Luer Lock inlet and outlet connections provide secure, leak-free attachment during filtration operations
• Each filter arrives gamma-sterilized and individually packaged to maintain contamination-free conditions until use
• Sterile-ready configuration eliminates preparation steps for immediate use in biological sample processing applications

Quality assurance comes from the mixed cellulose ester composition that naturally resists protein adsorption during clarification operations. The 3.1 cm² filtration area processes routine laboratory sample volumes appropriately while the 0.45 µm pore size removes particulates without compromising biomolecule recovery. Double Luer Lock connections maintain secure attachment during processing while the sterile-ready configuration eliminates preparation time, supporting diverse applications across pharmaceutical, biotechnology, and analytical testing laboratories requiring reliable particulate removal with biomolecule preservation.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

29psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Diameter

20mm

Dimensions

23mmx25.2mm

Filtration Area

3.1cm²

Material

Mixed Cellulose Ester (MCE)

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

60°C

Pack Count

100

Pore Size (µm)

0.45

Sterility

Sterile

Weight

0.72

Wetability

Hydrophilic

• Cell Culture Media Clarification - Remove particulates from serum supplements and growth factors while maintaining protein integrity for cell culture systems
• Biological Buffer Filtration - Clarify phosphate buffers and reagent solutions to remove debris before use in protein assays or enzyme reactions
• Protein Solution Processing - Filter enzyme preparations and antibody solutions while preserving concentration through low-binding membrane chemistry
• HPLC Sample Preparation - Clarify biological extracts before injection to protect columns and reduce baseline noise in chromatographic separations
• Pharmaceutical QC Testing - Remove particulates from drug formulations and excipient solutions before UV-Vis or HPLC analysis in quality control
• Microbiological Media - Clarify complex media components containing particulates before dispensing into culture vessels in research laboratories