PTFE Capsule Filters - 2601
From HPLC mobile phase preparation to process gas venting, PTFE capsule filters handle the chemically aggressive applications where other membrane materials degrade or fail. Central to its design, the chemically inert PTFE membrane within the capsule housing resists degradation by virtually all organic solvents, strong acids, and alkaline solutions, enabling filtration of the most aggressive process fluids. The result is a filtration process that eliminates cleaning validation, reduces changeover time, and provides batch-to-batch consistency through factory-tested, integrity-verified devices.
Key PTFE Membrane Characteristics
- The 121 degree Celsius temperature limit ensures reliable capsule performance for ambient and moderately heated filtration applications.
- Chemical inertness of the PTFE membrane ensures that filtered solvents and gases pass through without extractable contamination, meeting the purity requirements of HPLC mobile phase preparation and analytical applications.
- PTFE membrane capsules resist degradation by virtually all organic solvents, strong acids, bases, and oxidizing agents, providing universal chemical compatibility for aggressive filtration applications.
- Rated for operating pressures up to 60 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
- The single-layer configuration delivers efficient filtration of clean solutions at lower differential pressures than dual-layer alternatives, supporting gravity-feed and low-pressure applications.
Key Capsule Construction Features
- Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
- Stepped hose barb design accommodates multiple tubing sizes on a single fitting, simplifying inventory management and enabling connection flexibility across different process configurations.
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
As single-use filtration continues to replace reusable housings across pharmaceutical and laboratory environments, your capsule filter selection determines both the quality of the filtrate and the efficiency of the workflow. If your workflow involves organic solvents, aggressive reagents, or process gas streams, the universal chemical resistance of PTFE membrane construction handles the harshest conditions your application presents. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.
Sterilization Guidance
Standard autoclave cycles at 121 degrees Celsius are compatible with the polypropylene housing and membrane assembly, allowing preparation for sterile applications at the point of use.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 13 psi (IPA)
- Capsule Format
- Polycap TF 36
- Compliance Standards
- ISO 9001
- Construction
- Polypropylene
- Diameter
- 3.6 cm
- Filling Bell (Yes/ No)
- No
- Filtration Area
- 430 cm²
- Holdup Volume
- 10 mL
- Inlet Connection
- 1/4 to 3/8 in. stepped barb
- Length
- 9.2 cm
- Material
- PTFE
- Max Batch Volume
- Medium-volume batch processing
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 121 °C
- Outlet Connection
- 1/4 to 3/8 in. stepped barb
- Pack Count
- 5
- Pore Size (µm)
- 0.2
- Prefilter (Yes/No)
- No
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- No
- Wettability
- Hydrophobic
- Solvent Recovery - Clarification of recycled organic solvents to remove particulates accumulated during previous processing operations.
- Tank Venting - Hydrophobic membrane barrier prevents microbial ingress while allowing pressure equalization in process tank headspaces.
- Air Filtration - Point-of-use filtration of compressed air and nitrogen gas streams supplying clean manufacturing environments.
- Vent Protection - Membrane barrier filtration for fermentation vessel exhaust and bioreactor off-gas systems in bioprocessing facilities.
- Chemical Processing - Filtration of strong acids, bases, and aggressive organic chemicals that degrade PES, PVDF, and nylon membranes.
- HPLC Preparation - Particle removal from organic and mixed mobile phases prior to high-performance liquid chromatography analysis.