PolyCap TF 36 PTFE Capsule Filter SKU: 2603

PTFE Capsule Filters - 2603

PTFE capsule filters provide chemically inert filtration for aggressive solvents, corrosive reagents, and gas streams that would compromise other membrane materials. Equally important, the chemically inert PTFE membrane within the capsule housing resists degradation by virtually all organic solvents, strong acids, and alkaline solutions, enabling filtration of the most aggressive process fluids. The outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key PTFE Membrane Characteristics

• Non-sterile configuration accommodates laboratory and industrial applications where the capsule filter serves a clarification or protection function rather than a sterilizing-grade barrier role.
• The hydrophobic PTFE membrane serves both liquid solvent filtration and sterile gas venting applications, with alcohol pre-wetting required only for aqueous solution processing.
• PTFE membrane capsules resist degradation by virtually all organic solvents, strong acids, bases, and oxidizing agents, providing universal chemical compatibility for aggressive filtration applications.
• Single-layer membrane construction provides direct, absolute retention at the rated pore size without the additional flow resistance introduced by upstream prefilter layers.
• The 10 milliliter holdup volume reflects the capsule's internal fluid path geometry, relevant to recovery calculations for precious samples and small-batch pharmaceutical formulations.

Key Capsule Construction Features

• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.

When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. To address this, for laboratories and production facilities filtering HPLC mobile phases, aggressive chemicals, or sterile gases, PTFE capsule filters provide the chemical inertness your purity standards demand. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Polypropylene construction throughout the device permits autoclave sterilization at standard conditions, enabling end-user preparation for sterile filtration applications as needed.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

3 psi (IPA)

Capsule Format

Polycap TF 36

Compliance Standards

ISO 9001

Construction

Polypropylene

Diameter

3.6 cm

Filling Bell (Yes/ No)

No

Filtration Area

430 cm²

Holdup Volume

10 mL

Inlet Connection

1/4 to 3/8 in. stepped barb

Length

9.2 cm

Material

PTFE

Max Batch Volume

Medium-volume batch processing

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

121 °C

Outlet Connection

1/4 to 3/8 in. stepped barb

Pack Count

5

Pore Size (µm)

1

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave

Vent (Yes/ No)

No

Wettability

Hydrophobic

• Chemical Processing - Filtration of strong acids, bases, and aggressive organic chemicals that degrade PES, PVDF, and nylon membranes.
• Air Filtration - Point-of-use filtration of compressed air and nitrogen gas streams supplying clean manufacturing environments.
• Tank Venting - Hydrophobic membrane barrier prevents microbial ingress while allowing pressure equalization in process tank headspaces.
• Solvent Recovery - Clarification of recycled organic solvents to remove particulates accumulated during previous processing operations.
• HPLC Preparation - Particle removal from organic and mixed mobile phases prior to high-performance liquid chromatography analysis.
• Vent Protection - Membrane barrier filtration for fermentation vessel exhaust and bioreactor off-gas systems in bioprocessing facilities.