PolyCap TC 150 Capsule Filter, 0.2/0.2um, w/ 1 1/2in Sanitary Inlet & Outlet SKU: 6704-9502

Polyethersulfone (PES) Capsule Filters - 6704-9502

PES capsule filters deliver the combination of high flow rates, low extractables, and validated retention performance that biopharmaceutical and laboratory workflows demand. The pleated PES membrane pack maximizes effective filtration area within the capsule housing, sustaining high flow rates through large batch volumes while inherent hydrophilicity ensures immediate wetting without alcohol pre-treatment. Accordingly, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Polyethersulfone (PES) Membrane Characteristics

The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.
Capsule holdup volume of 250 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.
Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.
PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
The prefilter-final filter combination within a single capsule housing provides graduated retention that extends device life when processing biological fluids with variable particulate loads.

Key Capsule Construction Features

Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
Tri-clamp compatible sanitary connections enable tool-free capsule installation and removal, minimizing changeover time in production-scale filtration operations.
Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.

Whether your process requires sterilizing-grade retention for a 500-milliliter bench trial or clarification capacity for a 100-liter production batch, the right capsule filter configuration eliminates the compromises between throughput, retention, and operational simplicity. Specifically, if your process involves aqueous biologicals, the ultra-low protein binding and broad pH compatibility of PES membrane construction protect your product while sustaining the flow rates your batch schedule requires. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Polypropylene construction throughout the device permits autoclave sterilization at standard conditions, enabling end-user preparation for sterile filtration applications as needed.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.