PolyCap TC 36 PES Capsule Filter SKU: 6714-3602

Polyethersulfone (PES) Capsule Filters - 6714-3602

PES capsule filters deliver the combination of high flow rates, low extractables, and validated retention performance that biopharmaceutical and laboratory workflows demand. The pleated PES membrane pack maximizes effective filtration area within the capsule housing, sustaining high flow rates through large batch volumes while inherent hydrophilicity ensures immediate wetting without alcohol pre-treatment. Consequently, the outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.

Key Polyethersulfone (PES) Membrane Characteristics

• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• Sterile capsule delivery eliminates the autoclave or in-line steam sterilization steps that add time and risk to aseptic manufacturing workflows.
• The inherently hydrophilic PES membrane wets immediately on contact with aqueous solutions, eliminating alcohol pre-flush steps and reducing both startup time and solvent waste.
• Capsule holdup volume of 70 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.

Key Capsule Construction Features

• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.

When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. For laboratories processing cell culture media, buffers, or biological preparations, PES capsule construction delivers the combination of low binding, high throughput, and validated retention that your quality system depends on. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Pre-sterilized packaging delivers the device ready for direct integration into aseptic workflows, eliminating the preparation time and validation requirements associated with user-performed sterilization.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40 psi

Burst Pressure (psi)

60 psi

Capsule Format

Polycap TC 36

Compliance Standards

ISO 9001; HIMA Challenge Test

Construction

Polypropylene

Diameter

3.6 cm

Filling Bell (Yes/ No)

No

Filtration Area

550 cm²

Holdup Volume

70 mL

Inlet Connection

1/4 to 3/8 in. stepped barb

Material

PES

Max Batch Volume

Medium-volume batch processing

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

121 °C

Outlet Connection

1/4 to 3/8 in. stepped barb

Pack Count

1

Pore Size (µm)

0.2

Pre-filter Pore Size

0.2

Prefilter (Yes/No)

Yes

Sterility

Sterile

Sterilization

Do not re-sterilize (autoclavable if sterility expires)

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.