PolyCap TC 36 PES Capsule Filter SKU: 6715-3682

Polyethersulfone (PES) Capsule Filters - 6715-3682

Ultra-low protein binding and broad pH compatibility from 1 to 14 make PES capsule filters the preferred membrane choice for processing biological solutions at production scale. Designed for laboratory performance, PES membrane chemistry delivers broad pH compatibility from 1 to 14, supporting filtration of buffers, media, and cleaning solutions through a single capsule platform without material degradation. With this in mind, the outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.

Key Polyethersulfone (PES) Membrane Characteristics

• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• Ultra-low protein binding characteristics of the PES membrane minimize adsorptive losses, preserving the concentration and biological activity of filtered proteins, antibodies, and growth factors.
• The 60 psi maximum pressure rating accommodates the differential pressures generated during filtration of particle-laden solutions as the membrane progressively loads.
• Dual-layer membrane construction combines a coarser upstream prefilter with a finer downstream retention membrane, maximizing dirt-holding capacity within a single capsule device.
• Rated for continuous operation at temperatures up to 121 degrees Celsius, the capsule maintains structural integrity and retention performance across the normal process temperature range.

Key Capsule Construction Features

• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.

Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. For laboratories processing cell culture media, buffers, or biological preparations, PES capsule construction delivers the combination of low binding, high throughput, and validated retention that your quality system depends on. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Sealed sterile packaging preserves validated sterility throughout storage and transport, providing a documented sterile barrier that is ready for use at the point of need.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40 psi

Burst Pressure (psi)

60 psi

Capsule Format

Polycap TC 36

Compliance Standards

ISO 9001; HIMA Challenge Test

Construction

Polypropylene

Diameter

3.6 cm

Filling Bell (Yes/ No)

Yes

Filtration Area

550 cm²

Holdup Volume

70 mL

Inlet Connection

1/4 to 3/8 in. stepped barb

Material

PES

Max Batch Volume

Medium-volume batch processing

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

121 °C

Outlet Connection

1/4 to 3/8 in. stepped barb

Pack Count

1

Pore Size (µm)

0.2

Pre-filter Pore Size

0.8

Prefilter (Yes/No)

Yes

Sterility

Sterile

Sterilization

Do not re-sterilize (autoclavable if sterility expires)

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.