PolyCap TC 75 Capsule Filter, 1.0/1.0um, Sterile, w/ 1/2in SB Inlet & Outlet SKU: 6717-7510

Polyethersulfone (PES) Capsule Filters - 6717-7510

PES capsule filters deliver the combination of high flow rates, low extractables, and validated retention performance that biopharmaceutical and laboratory workflows demand. Designed for laboratory performance, the pleated PES membrane pack maximizes effective filtration area within the capsule housing, sustaining high flow rates through large batch volumes while inherent hydrophilicity ensures immediate wetting without alcohol pre-treatment. To this end, the outcome is a validated filtration barrier that arrives ready for process integration, supporting the single-use manufacturing strategies adopted by modern pharmaceutical and biotechnology facilities.

Key Polyethersulfone (PES) Membrane Characteristics

• PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.
• Dual-layer construction protects the sterilizing-grade final membrane from premature plugging, delivering sustained flow rates through feed streams that would rapidly block single-layer devices.
• Internal holdup volume of 125 milliliters minimizes sample loss during capsule filtration, a critical consideration when processing expensive biologics or limited-volume preparations.
• Maximum operating temperature of 121 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.

Key Capsule Construction Features

• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
• Stepped hose barb connections accommodate tubing with inner diameters from 1/4 to 1/2 inch, providing secure push-fit attachment without requiring clamps or specialized fittings.

Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. If your process involves aqueous biologicals, the ultra-low protein binding and broad pH compatibility of PES membrane construction protect your product while sustaining the flow rates your batch schedule requires. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

Sterilization Guidance

Factory sterilization ensures the device is ready for immediate use in aseptic applications, with validated sterility maintained through the sealed packaging until the labeled expiration date.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

16 psi

Burst Pressure (psi)

60 psi

Capsule Format

Polycap TC 75

Compliance Standards

ISO 9001; HIMA Challenge Test

Construction

Polypropylene

Diameter

7.5 cm

Filling Bell (Yes/ No)

No

Filtration Area

1100 cm²

Holdup Volume

125 mL

Inlet Connection

3/8 to 1/2 in. stepped barb

Material

PES

Max Batch Volume

Large-volume batch processing

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

121 °C

Outlet Connection

3/8 to 1/2 in. stepped barb

Pack Count

1

Pore Size (µm)

1

Pre-filter Pore Size

1

Prefilter (Yes/No)

Yes

Sterility

Sterile

Sterilization

Do not re-sterilize (autoclavable if sterility expires)

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.