Polyethersulfone (PES) Capsule Filters - 6717-9502
When processing aqueous biologicals at volumes beyond syringe filter capacity, PES capsule filters provide the throughput and recovery performance that bench-scale devices cannot match. Manufactured to exacting specifications, asymmetric PES membrane construction captures contaminants at the upstream surface while maintaining open pore channels beneath, extending capsule service life and reducing the frequency of mid-batch device changes. With this in mind, the result is a filtration process that eliminates cleaning validation, reduces changeover time, and provides batch-to-batch consistency through factory-tested, integrity-verified devices.
Key Polyethersulfone (PES) Membrane Characteristics
- PES membrane capsules deliver broad pH compatibility from 1 to 14, accommodating the full range of buffers, media, and cleaning solutions encountered in biopharmaceutical processing.
- PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
- An integrated prefilter layer upstream of the final membrane captures coarse particulates before they reach the sterilizing-grade surface, extending capsule throughput and service life.
- Capsule holdup volume of 250 milliliters represents the fluid retained within the device after filtration, an important factor when calculating yield for high-value pharmaceutical products.
- Rated for operating pressures up to 60 psi, the capsule housing withstands the system pressures encountered in peristaltic pump, pressure vessel, and gravity-feed filtration configurations.
Key Capsule Construction Features
- The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
- Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
- Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
When your filtration protocol calls for a validated, integrity-testable barrier that arrives ready to connect and begins filtering immediately, the capsule format delivers that capability without the overhead of traditional filter assemblies. In these cases, if your process involves aqueous biologicals, the ultra-low protein binding and broad pH compatibility of PES membrane construction protect your product while sustaining the flow rates your batch schedule requires. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.
Sterilization Guidance
Sealed sterile packaging preserves validated sterility throughout storage and transport, providing a documented sterile barrier that is ready for use at the point of need.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 40 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- Polycap TC 150
- Compliance Standards
- ISO 9001; HIMA Challenge Test
- Construction
- Polypropylene
- Diameter
- 15 cm
- Filling Bell (Yes/ No)
- No
- Filtration Area
- 2200 cm²
- Holdup Volume
- 250 mL
- Inlet Connection
- 3/8 to 1/2 in. stepped barb
- Material
- PES
- Max Batch Volume
- Large-volume batch processing
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 121 °C
- Outlet Connection
- 3/8 to 1/2 in. stepped barb
- Pack Count
- 1
- Pore Size (µm)
- 0.2
- Pre-filter Pore Size
- 0.2
- Prefilter (Yes/No)
- Yes
- Sterility
- Sterile
- Sterilization
- Do not re-sterilize (autoclavable if sterility expires)
- Vent (Yes/ No)
- No
- Wettability
- Hydrophilic
- Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.
- Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
- Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
- Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
- Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
- Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.