PolyCap TC 150 Capsule Filter, 0.8/0.2um, Sterile, 1/2in SB In & Outlet w/ Filling Bell SKU: 6718-9582

Polyethersulfone (PES) Capsule Filters - 6718-9582

Ultra-low protein binding and broad pH compatibility from 1 to 14 make PES capsule filters the preferred membrane choice for processing biological solutions at production scale. Optimized for laboratory use, asymmetric PES membrane construction captures contaminants at the upstream surface while maintaining open pore channels beneath, extending capsule service life and reducing the frequency of mid-batch device changes. In effect, the outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.

Key Polyethersulfone (PES) Membrane Characteristics

• The asymmetric pore structure of PES membranes captures contaminants at the upstream surface while maintaining open downstream channels, extending capsule throughput before reaching differential pressure limits.
• Pre-sterilized capsule packaging maintains sterility through storage, transport, and connection, providing a validated sterile barrier at the point of use.
• Maximum operating temperature of 121 degrees Celsius supports filtration of warm solutions and accommodates the thermal conditions present in process environments.
• PES capsule filters achieve flow rates that support large-batch processing without the mid-run device changes that disrupt sterile workflows and introduce contamination risk.
• PES membrane construction supports integrity testing by forward flow, bubble point, or pressure decay methods, providing the post-use verification required by pharmaceutical quality systems.

Key Capsule Construction Features

• The sealed polypropylene housing is individually integrity-tested during manufacturing, verifying membrane installation and housing seal quality before the device leaves the production facility.
• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
• Stepped hose barb design accommodates multiple tubing sizes on a single fitting, simplifying inventory management and enabling connection flexibility across different process configurations.
• Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.

Your laboratory's filtration throughput depends not only on membrane retention characteristics but on the practical factors of device connection, priming, and changeover that capsule filters are specifically engineered to optimize. Addressing this directly, for laboratories processing cell culture media, buffers, or biological preparations, PES capsule construction delivers the combination of low binding, high throughput, and validated retention that your quality system depends on. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

Sterilization Guidance

Sealed sterile packaging preserves validated sterility throughout storage and transport, providing a documented sterile barrier that is ready for use at the point of need.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40 psi

Burst Pressure (psi)

60 psi

Capsule Format

Polycap TC 75

Compliance Standards

ISO 9001; HIMA Challenge Test

Construction

Polypropylene

Diameter

15 cm

Filling Bell (Yes/ No)

Yes

Filtration Area

2200 cm²

Holdup Volume

250 mL

Inlet Connection

3/8 to 1/2 in. stepped barb

Material

PES

Max Batch Volume

Large-volume batch processing

Maximum Operating Pressure

60 psi

Maximum Operating Temperature (°C)

121 °C

Outlet Connection

1/4 to 3/8 in. stepped barb

Pack Count

1

Pore Size (µm)

0.2

Pre-filter Pore Size

0.8

Prefilter (Yes/No)

Yes

Sterility

Sterile

Sterilization

Do not re-sterilize (autoclavable if sterility expires)

Vent (Yes/ No)

No

Wettability

Hydrophilic

• Reagent Filtration - Removal of particulates and contaminants from laboratory reagents and process solutions before downstream use.
• Serum Processing - Capsule filtration of animal sera and biological supplements for cell culture and diagnostic reagent applications.
• Process Intermediates - In-line capsule filtration of pharmaceutical intermediates with validated retention and low adsorptive losses.
• Water Purification - Membrane-grade filtration of purified water and water-for-injection systems in pharmaceutical manufacturing facilities.
• Buffer Processing - Large-volume filtration of pharmaceutical buffers and process solutions with broad pH compatibility across pH 1-14.
• Biologics Protection - Ultra-low protein binding preserves antibody and growth factor concentrations through the membrane retention step.