GD/X 25mm Syringe Filter, Cellulose Acetate Filteration Medium, 0.45um (150 pcs)
Whatman SKU: 6880-2504

Whatman GD/X Cellulose Acetate (CA) Syringe Filters, 0.45 µm, 25 mm, 150/Pk - 6880-2504

Whatman stages multiple glass fiber layers inside the GD/X cartridge to intercept particles in progressive steps, leaving only the smallest fraction to reach the tightly rated final membrane. A syringe filter dispenses filtrate directly into an autosampler vial, without the intermediate collection vessel a bulk vacuum filtration setup typically needs. The cellulose acetate membrane takes up aqueous buffers on contact while binding less protein than mixed cellulose ester of similar size and maintains a particle cutoff at that rating. The polypropylene housing presses snugly against the membrane during the pass and maintains a low-dead-volume internal flow path. Where small-volume samples must reach the instrument clean, low hold-up volume keeps sample loss minimal while the instrument stays protected from particulate damage.

Membrane Characteristics

• Dilute samples retain their true, unadsorbed concentration through the membrane
• Smooth membrane face with even pore distribution across the active filtration area
• Biologically nontoxic cellulose ester provides a clean filtration surface
• Native surface hydroxyl groups sustain a hydration layer ahead of protein contact
• Lot-to-lot uniformity in pore distribution produces consistent retention across batches

Housing Characteristics

• Dilute aqueous acids, bases, and alcohols used in sample prep do not degrade the polypropylene housing
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate
• The seal formed against the membrane blocks bypass at rated operating pressure
• Plasticizer-free polyolefin construction keeps the fluid path clean

A clean particulate separation keeps your aqueous sample preparation dependable. Consistent aqueous clarification clears particulates without slowing your bench routine across the buffers and reagents your day-to-day prep depends on. Standardize your filtration purchases across every method with volume pricing and documentation from the Tisch Scientific team.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.0 bar (29 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.6cm²

Flow Rate

29

Holdup Volume

1.4ml

Material

Cellulose Acetate

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

150

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

Glass Microfiber (GMF)

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Dissolution Testing - Clarifies drug-release samples of undissolved particulates pulled from dissolution vessels, ensuring accurate potency results.
• PCR Sample Prep - CA's very low non-specific binding ensures nucleic acids and buffer components pass through cleanly ahead of PCR amplification.
• IC Sample Prep - CA membrane clarifies aqueous samples before IC injection, protecting guard columns and extending column life without analyte loss.
• Urinalysis Prep - CA clarifies urine samples by removing particulates ahead of automated urinalysis without altering biochemical composition.
• Saline Solution Prep - CA membrane filters saline and physiological buffer solutions, removing particulates for in vitro assays and formulation use.
• Allergen Testing Prep - CA's low-binding surface cleanly passes allergen proteins from aqueous food extracts ahead of ELISA allergen quantitation.