GD/X 25mm Sterile Syringe Filter, PES, 0.45um (50 pcs)
Whatman SKU: 6896-2504

Whatman GD/X Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 50/Pk - 6896-2504

Whatman fits more prefiltration capacity into the GD/X housing without enlarging it, a space-efficient answer for samples too demanding for one filtration pass. A syringe filter's small hold-up volume limits sample loss, a meaningful difference when working with a limited or precious sample. PES stays stable across the full pH 1 to 14 range while needing a surface treatment before its polysulfone base wets and keeps that modified surface active throughout use. Low-extractable polypropylene keeps sample purity intact through the filtration pass while pressing snugly against the membrane during the pass and maintains a low-dead-volume internal flow path. Where bench-scale prep must move quickly from one sample to the next, each sample starts as clean as the last without a carry-over risk or a cleaning step between uses.

Membrane Characteristics

• Non-hydrogen-bonding surface avoids the polar adsorption nylon's amide backbone causes
• Sulfone backbone's hydrolytic stability tolerates repeated autoclave steam sterilization cycles
• Chemical breadth spans alcohols, glycols, and aqueous buffers
• Mechanical strength keeps the matrix intact under vacuum or pressure
• Absolute pore size rating holds consistent across every lot

Housing Characteristics

• Polypropylene housing tolerates ethylene oxide gas sterilization cycles without softening or dimensional distortion.
• PP housing rated to 121°C holds its geometry through high-temperature sample preparation and processing.
• Dilute aqueous acids, bases, and alcohols used in sample prep do not degrade the polypropylene housing
• Minimal ionic background from the polypropylene housing supports ion chromatography and trace-metal ICP-MS sample preparation.

A clean particulate separation keeps your aqueous sample preparation dependable. Consistent aqueous clarification clears particulates without slowing your bench routine the same way every time you run it. Request Whatman's lot documentation and performance history to support your protocol validation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.3 bar (33 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.6cm²

Flow Rate

30

Holdup Volume

1.4ml

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

50

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

Glass Microfiber (GMF)

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Organic Carbon Testing - Clarifies water samples ahead of DOC and UV254 analysis while keeping organic carbon adsorption to the membrane minimal.
• Pesticide Residue Testing - PES membranes improve polar pesticide recovery in food-safety LC-MS/MS testing versus hydrogen-bonding nylon.
• Nucleic Acid Recovery - Processes DNA and RNA extracts with minimal nucleic acid adsorption, preserving yield on the hydrophilic PES surface.
• Serum Filtration - Clarifies serum and plasma samples quickly while retaining critical proteins needed for accurate downstream analytical testing.
• Biological Assays - Protects sensitive enzymatic and antibody-based assays from particulate interference without adsorbing critical reagents.
• Sample Recovery - Minimizes sample loss in low-protein-binding applications, delivering high yield for precious or rare biological specimens.