GD/XP Syringe Filter, PVDF Filteration Medium, 0.45um (150 pcs)
Whatman SKU: 6972-2504

Whatman GD/XP PVDF Syringe Filters, 0.45 µm, 25 mm, 150/Pk - 6972-2504

Whatman stages a coarse and a fine polypropylene layer ahead of the rated membrane in the GD/XP cartridge, clearing particulate load before it reaches metals-analysis-grade filtrate. Many syringe filters ship with lot-specific quality documentation, giving analysts traceability that an ad hoc bulk filtration setup typically lacks. Hydrophilic PVDF suits HPLC sample preparation with immediate, reliable uptake and clarifies samples at the rated pore size. The polypropylene housing presses snugly against the membrane during the pass and keeps the sample chemically unaltered across the pass. When chromatographic methods demand particle-free injections, the column stays clean from run to run, protecting method performance and column life.

Membrane Characteristics

• Absolute pore rating ensures reproducible results between test runs
• Gamma irradiation sterilization causes no chain scission unlike polypropylene membranes
• Cast membrane structure releases no fibers, unlike depth-media prefilters
• Mechanically durable membrane holds integrity under filtration pressure
• Protein and peptide sample loss to adsorption stays minimal

Housing Characteristics

• Rigid polypropylene body maintains its geometry through routine filtration pressure
• Minimal extractable release from the housing supports sensitive analytical work downstream
• Polypropylene housing withstands operating temperatures up to 121°C without softening or dimensional distortion.
• Inert polyolefin wall contributes minimal sample adsorption to the filtrate

Filtering buffers, reagents, and aqueous samples keeps your preparation moving and consistent. General-purpose aqueous filtration supports the sample types you handle every day across your water-analysis and general analytical workflows. Ask our customer support technicians for chemical compatibility guidance on your specific filtration application.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.6cm²

Holdup Volume

1.4ml

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

150

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

Polypropylene (10µm + 5µm)

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Dissolution Testing - Removes undissolved particles from timed USP 711 dissolution aliquots, preventing skewed potency and release results.
• Trace Analysis - Prevents non-specific binding in trace analysis, keeping low-concentration analytes in solution for reliable detection.
• Microbiome Sampling - Concentrates waterborne microbial cells on a low-binding membrane ahead of DNA extraction and metagenomics sequencing.
• Biological Samples - Clarifies protein-rich solutions without loss of target molecules, preserving sample integrity for critical downstream assays.
• Pharmaceutical QC - Supports routine quality control testing by reliably filtering mild organic solvent mixtures and drug formulations daily.
• Beverage QC - Clarifies wine, beer, and juice samples ahead of HPLC testing for organic acids, sugars, and preservatives.