GD/XP Syringe Filter, PES, 0.45um (150 pcs)
Whatman SKU: 6994-2504

Whatman GD/XP Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 150/Pk - 6994-2504

Whatman fits two graded polypropylene prefilter layers into the GD/XP housing, a construction that serves samples where trace-metal accuracy depends on what the filter itself contributes to the result. A syringe filter's small hold-up volume limits sample loss, a meaningful difference when working with a limited or precious sample. PES handles strong bases and oils across a broad aqueous range and pairs fast flow with reduced protein adsorption. Thermal-bonded PP construction leaves no seam for sample to bypass the membrane while resisting degradation from routine sample matrices and keeps the sample chemically unaltered across the pass. When chromatographic methods demand particle-free injections, the column stays clean from run to run, protecting method performance and column life.

Membrane Characteristics

• Compatibility spans both nucleic acid and protein-based filtration
• Non-hydrogen-bonding surface avoids the polar adsorption nylon's amide backbone causes
• Non-ionic surface avoids charge-driven protein binding of positively and negatively charged membrane types
• Pore structure integrity holds through autoclave cycles up to 126°C
• Chemical breadth spans alcohols, glycols, and aqueous buffers

Housing Characteristics

• Minimal intrinsic autofluorescence from the polypropylene housing supports background-sensitive fluorescence-based assay work downstream.
• Optimized internal geometry minimizes backpressure in service
• Standardized luer connection geometry provides secure engagement with standard syringe tips
• Impact-tolerant polypropylene body withstands routine bench handling without damage

A clean particulate separation keeps your aqueous sample preparation dependable. Consistent aqueous clarification clears particulates without slowing your bench routine across the buffers and reagents your day-to-day prep depends on. Ask our team about Whatman's performance credentials before you commit to a filtration standard requiring documented quality.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.3 bar (33 psi)

Connection Type

Luer-Lok/ Luer Slip

Diameter

25mm

Filtration Area

4.91cm²

Material

Polyethersulfone (PES)

Pack Count

150

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Groundwater Tests - Clarifies groundwater samples ahead of ICP-MS trace element testing while keeping metal backgrounds minimal.
• Serum Filtration - Clarifies serum and plasma samples quickly while retaining critical proteins needed for accurate downstream analytical testing.
• Biological Assays - Protects sensitive enzymatic and antibody-based assays from particulate interference without adsorbing critical reagents.
• Pesticide Residue Testing - PES membranes improve polar pesticide recovery in food-safety LC-MS/MS testing versus hydrogen-bonding nylon.
• Trace Metal Prep - Processes samples ahead of trace metal analysis using a low-extractable prefilter that avoids added background metal ions.
• PFAS Water Testing - PES filters process aqueous samples for EPA Method 1633A PFAS testing without added fluorinated background.