GD/XP Syringe Filter, PES, 0.45um (150 pcs)
Whatman SKU: 6995-2504

Whatman GD/XP Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 150/Pk - 6995-2504

Whatman stages a coarse and a fine polypropylene layer ahead of the rated membrane in the GD/XP cartridge, clearing particulate load before it reaches metals-analysis-grade filtrate. Syringe filters span a wide range of membrane chemistries and pore sizes, so the format can be matched to the sample matrix and solvent system in use. PES's native polysulfone needs a surface treatment before it wets while tolerating aliphatic alcohols, glycols, and aqueous buffers and maintains absolute retention accuracy at that pore rating. The polypropylene housing maintains its geometry through sample runs up to 121°C while routing flow to minimize backpressure in service and stands firm against aqueous acids, bases, and alcohols during regular handling. When chromatographic methods demand particle-free injections, the column stays clean from run to run, protecting method performance and column life.

Membrane Characteristics

• Sulfone backbone's hydrolytic stability tolerates repeated autoclave steam sterilization cycles
• DNA and RNA pass through with negligible adsorptive loss
• Antibody and protein samples pass through PES with minimal adsorptive loss
• Inherent hydrophilicity allows instant aqueous wetting with no pre-wetting step
• Aromatic sulfone backbone underlies stability across the full pH range

Housing Characteristics

• Housing retains dimensional stability and seal integrity through elevated-temperature operation up to 121°C.
• Optimized internal geometry minimizes backpressure in service
• Polypropylene density near 0.90 g/cm3 keeps housing weight low relative to denser engineering plastics
• Medical-grade polypropylene with broad chemical compatibility

Clarify your routine aqueous samples in a single pass and cut down on juggling multiple filter types at the bench. General-purpose aqueous filtration supports the sample types you handle every day so you can standardize one filter across most aqueous methods. Start a live chat with our customer support technicians for quick answers to your compatibility, sizing, and sterility questions.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.3 bar (33 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.6cm²

Holdup Volume

1.4ml

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

150

Pore Size (µm)

0.45

Prefilter (Yes/No)

Yes

Prefilter Material

Polypropylene (10µm + 5µm)

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Trace Metal Prep - Processes samples ahead of trace metal analysis using a low-extractable prefilter that avoids added background metal ions.
• Serum Filtration - Clarifies serum and plasma samples quickly while retaining critical proteins needed for accurate downstream analytical testing.
• Organic Carbon Testing - Clarifies water samples ahead of DOC and UV254 analysis while keeping organic carbon adsorption to the membrane minimal.
• Biological Assays - Protects sensitive enzymatic and antibody-based assays from particulate interference without adsorbing critical reagents.
• Sample Recovery - Minimizes sample loss in low-protein-binding applications, delivering high yield for precious or rare biological specimens.
• PFAS Water Testing - PES filters process aqueous samples for EPA Method 1633A PFAS testing without added fluorinated background.