Pura Disc 25mm PVDF Syringe Filters, 0.45um, 50 Pk
Whatman SKU: 6746-2504

Whatman Puradisc PVDF Syringe Filters, 0.45 µm, 25 mm, 50/Pk - 6746-2504

Whatman applies the same process controls across its filtration portfolio, verifying rated performance at the production lot level. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. The hydrophilic PVDF membrane draws aqueous mobile phases through without pre-wetting while holding up to alcohols and mild hydrocarbon solvents and holds consistent absolute retention at the rated pore size. The polypropylene housing holds a reliable seal against the membrane edge and resists aqueous acids, bases, and alcohols. When method reproducibility rests on consistent sample prep, syringe filtration holds that standard injection after injection.

Technical Specifications

• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Absolute pore size rating gives consistent results across protocols
• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Mechanically durable membrane holds integrity under filtration pressure
• Thin membrane structure sustains high flow for fast sample throughput

Housing Specifications

• Optimized internal geometry minimizes backpressure in service
• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Medical-grade polypropylene with broad chemical compatibility
• Low extractable contribution protects sensitive downstream analyses

Upstream clarification pays for itself by keeping your columns clear and your analytical day on schedule. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Contact Tisch Scientific for technical guidance on selecting the right filtration product for your specific application requirements.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

50

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• HPLC Sample Prep - PVDF provides a great balance of chemical compatibility and low background noise for sensitive UV detection
• Western Blotting - Optimized for often used in preparing samples for downstream blotting techniques where purity is paramount
• Clarification of Biologicals - Perfect for removing particulates from biological fluids without removing the target biomolecules
• Protein Analysis - Ultra-low protein binding ensures that your expensive protein samples are not lost to the filter matrix
• General Laboratory Filtration - Increases workflow efficiency by protecting analytical instruments without sacrificing flow rates
• Biological Fluid Analysis - Protects sensitive downstream instruments from removing particulates that can cause system failure