Pura Disc 25mm PVDF Syringe Filters, 0.45um, 50 Pk
Whatman SKU: 6746-2504

Whatman Puradisc PVDF Syringe Filters, 0.45 µm, 25 mm, 50/Pk - 6746-2504

Whatman's filtration expertise, refined across a century-plus of disciplined manufacturing, has made its name synonymous with laboratory-grade quality worldwide. Syringe filters span a wide range of membrane chemistries and pore sizes, so the format can be matched to the sample matrix and solvent system in use. The PVDF membrane tolerates common chromatography solvents without degradation while keeping HPLC analytes from adhering to the pore surface and suits HPLC sample preparation with immediate, reliable uptake. The polypropylene housing resists aqueous acids, bases, and alcohols in routine use while keeping sample purity intact through the filtration pass and presses snugly against the membrane during the pass. When chromatographic methods demand particle-free injections, the column stays clean from run to run, protecting method performance and column life.

Technical Specifications

• Fluoropolymer chemistry resists microbial and fungal degradation
• Vapor-phase hydrogen peroxide decontamination cycles leave the membrane intact
• Cast membrane structure releases no fibers, unlike depth-media prefilters
• Low extractables preserve a clean chromatographic baseline
• Adsorptive loss of HPLC analytes stays immeasurably low

Housing Specifications

• Minimal ionic background from the polypropylene housing supports ion chromatography and trace-metal ICP-MS sample preparation.
• PP housing rated to 121°C holds its geometry through high-temperature sample preparation and processing.
• Plasticizer-free polyolefin construction keeps the fluid path clean
• Polypropylene density near 0.90 g/cm3 keeps housing weight low relative to denser engineering plastics

Clarify your routine aqueous samples in a single pass and cut down on juggling multiple filter types at the bench. Consistent aqueous clarification clears particulates without slowing your bench routine the same way every time you run it. Bulk pricing kicks in on larger filtration orders, so ask the Tisch Scientific team for a quote.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

50

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Spectroscopy Prep - Provides optical clarity and low background interference, ideal for UV-Vis and fluorescence sample preparation work.
• Water Quality Monitoring - Clarifies environmental and drinking water samples ahead of turbidity, ion, or contaminant testing in monitoring programs.
• Microbiome Sampling - Concentrates waterborne microbial cells on a low-binding membrane ahead of DNA extraction and metagenomics sequencing.
• Beverage QC - Clarifies wine, beer, and juice samples ahead of HPLC testing for organic acids, sugars, and preservatives.
• Pre-Blot Sample Prep - Ensures ultra-low protein binding for maximum sample recovery ahead of sensitive immunodetection protocols and assays.
• Trace Analysis - Prevents non-specific binding in trace analysis, keeping low-concentration analytes in solution for reliable detection.