Whatman
Pura Disc 25mm PVDF Syringe Filters, 0.45um, 50 Pk SKU: 6746-2504

Polyvinylidene Difluoride (PVDF) Syringe Filters, 0.45µm, 25mm - 6746-2504

For researchers requiring consistent baselines in HPLC and dissolution testing, the Polyvinylidene Difluoride (PVDF) Whatman Puradisc, 25mm, Polyvinylidene Difluoride Syringe Filter, 0.45µm 50/pk offers a robust solution for extending instrument life. At the core of the device is a uniform Polyvinylidene Difluoride (PVDF) matrix, delivering high dirt-loading capacity and reliable exclusion of interfering particles. Complementing the membrane's purity, the housing's thermal bonding eliminates the need for adhesives, removing a common source of extractable contamination. Meeting the needs of regulated environments, this series supports compliance with stringent purity protocols across pharmaceutical and environmental applications.

Key Polyvinylidene Difluoride (PVDF) Membrane Characteristics

• Polyvinylidene Difluoride (PVDF) membrane with hydrophobic or hydrophilic affinity
• Ultra-Low Protein Binding characteristics
• Excellent resistance to HPLC solvents and oxidation
• High flow rates for clarified solutions
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lok/ Luer Slip for secure fitting
• 4.2cm² effective filtration area
• <100µl holdup volume to minimize sample loss

By selecting a filter that matches the exact chemical nature of your samples, you ensure that your workflow remains uninterrupted by membrane failures. You can rely on the certified integrity of these units to protect your critical samples and instrumentation from damaging contaminants. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

50

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wetability

Hydrophobic

• HPLC Sample Prep - PVDF provides a great balance of chemical compatibility and low background noise for sensitive UV detection
• Western Blotting - Optimized for often used in preparing samples for downstream blotting techniques where purity is paramount
• Clarification of Biologicals - Perfect for removing particulates from biological fluids without removing the target biomolecules
• Protein Analysis - Ultra-low protein binding ensures that your expensive protein samples are not lost to the filter matrix
• General Laboratory Filtration - Increases workflow efficiency by protecting analytical instruments without sacrificing flow rates
• Biological Fluid Analysis - Protects sensitive downstream instruments from removing particulates that can cause system failure