Pura Disc 25mm PVDF Syringe Filters, 0.45um, 1000 Pk
Whatman SKU: 6749-2504

Whatman Puradisc PVDF Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 6749-2504

Whatman applies over a century of filtration media expertise, manufacturing under the quality standards that established its products as global laboratory references. A syringe filter holds its membrane in a leak-tight housing for clarification at the bench. PVDF holds up to alcohols and mild hydrocarbon solvents and draws aqueous mobile phases through without pre-wetting. The polypropylene housing routes flow to minimize backpressure in service while resisting aqueous acids, bases, and alcohols and prevents sample bypass under rated operating pressure. When sterile or particle-free preparation matters at the bench, the syringe filter delivers it with minimal added handling.

Technical Specifications

• Thin membrane structure sustains high flow for fast sample throughput
• Mechanically durable membrane holds integrity under filtration pressure
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons
• Low extractables preserve a clean chromatographic baseline
• Ultra-low protein binding preserves dilute analytes for maximum recovery

Housing Specifications

• Thermal-bonded construction keeps adhesives out of the fluid path
• Medical-grade polypropylene with broad chemical compatibility
• Low extractable contribution protects sensitive downstream analyses
• Resists aqueous acids, bases, and alcohols in routine sample prep

Removing particulates from your buffers and mobile phases extends column life and keeps your baselines steady. Upstream buffer clarification keeps avoidable particulates out of your flow path before they reach the column inlet or detector. Ask our friendly customer service team to confirm the pore size, membrane, and sterility options your filtration application calls for.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Western Blotting - Optimized for use in preparing samples for downstream blotting techniques where purity is paramount
• HPLC Sample Prep - PVDF provides a great balance of chemical compatibility and low background noise for sensitive UV detection
• Clarification of Biologicals - Perfect for removing particulates from biological fluids without removing the target biomolecules
• Protein Analysis - Ultra-low protein binding ensures that your expensive protein samples are not lost to the filter matrix
• Biological Fluid Analysis - Protects sensitive downstream instruments from removing particulates that can cause system failure
• Quality Control Testing - Optimized for delivering reproducible results by removing particulates in standard pharmaceutical protocols