Pura Disc 25mm Nylon Syringe Filters, 0.45um, 500 Pk
Whatman SKU: 6752-2504

Whatman Puradisc Nylon Syringe Filters, 0.45 µm, 25 mm, 500/Pk - 6752-2504

Whatman has built such a strong track record in published methods that laboratories default to citing its name in standardized protocols. Individually packaged and pre-tested, a syringe filter needs no functional check before use the way a shared reusable holder does. The nylon membrane comes in a non-sterile format for routine analytical preparation and accepts water-based samples without surfactant conditioning. Polypropylene construction resists chemical degradation from routine sample matrices and sustains its dimensional form through high-temperature filtration workflows. Where small-volume samples must reach the instrument clean, low hold-up volume keeps sample loss minimal while the instrument stays protected from particulate damage.

Technical Specifications

• Compatible with most HPLC mobile phases for sample clarification
• Absolute pore size rating holds consistent across every protocol
• Non-fibrous membrane structure resists media shedding into the filtrate
• Solvent compatibility extends to both acetonitrile and methanol
• Non-sterile format suits HPLC and GC sample clarification

Housing Specifications

• Polypropylene density near 0.90 g/cm3 keeps housing weight low relative to denser engineering plastics
• Standardized luer connection geometry provides secure engagement with standard syringe tips
• Minimal intrinsic autofluorescence from the polypropylene housing supports background-sensitive fluorescence-based assay work downstream.
• Thermal-bonded construction keeps adhesives out of the fluid path

Clarify your routine aqueous samples in a single pass and cut down on juggling multiple filter types at the bench. Consistent aqueous clarification clears particulates without slowing your bench routine the same way every time you run it. Ask our customer support technicians for chemical compatibility guidance on your specific filtration application.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.0 bar (29 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

500

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Chemical Analysis - Withstands aggressive bases and alcohols, ideal for tough chemical compatibility filtration challenges in routine analysis.
• GC Sample Prep - Clarifies aqueous and organic extracts ahead of gas chromatography injection, protecting inlets from particulate fouling.
• Veterinary Drug Residue Testing - Clarifies meat, milk, and egg extracts ahead of LC-MS/MS screening for drug residues in food-safety laboratories.
• Biofuel Particulate Testing - Removes particulate debris from biodiesel and fuel samples ahead of chromatographic QC analysis in fuel testing labs.
• Ink and Dye Filtration - Filters aqueous and solvent-based inks and dyes, removing pigment agglomerates ahead of color strength analysis.
• IC Column Protection - Clarifies aqueous samples ahead of anion and cation analysis, guarding ion-exchange columns against particulate fouling.