Whatman
Pura Disc 25mm Nylon Syringe Filters, 0.45um, 500 Pk SKU: 6752-2504

Nylon (NY) Syringe Filters, 0.45µm, 25mm - 6752-2504

For researchers requiring consistent baselines in HPLC and dissolution testing, the Nylon Whatman Puradisc, 25mm, Syringe Filter, 0.45µm 500/pk offers a robust solution for extending instrument life. To ensure analytical precision, the unit is constructed with a high-grade Nylon membrane providing a consistent 0.45 cutoff that passes only your target analyte. Complementing the membrane's purity, the housing's thermal bonding eliminates the need for adhesives, removing a common source of extractable contamination. Ultimately, this rigorous attention to manufacturing quality ensures batch-to-batch reproducibility, allowing laboratories to standardize their workflows with total confidence.

Key Nylon Membrane Characteristics

• Nylon membrane with hydrophilic affinity
• High Protein Binding characteristics
• Compatible with aqueous (non-acidic) solutions and most organic solvents
• High binding matrix: Avoid use with biological samples where yield is critical; incompatible with acidic solutions (pH < 3)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lok/ Luer Slip for secure fitting
• 4.2cm² effective filtration area
• <100µl holdup volume to minimize sample loss

When you integrate these filters into your daily standard operating procedures, you are choosing a workflow that prioritizes efficiency without compromising results. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.0 bar (29 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

500

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wetability

Hydrophilic

• HPLC Sample Preparation - Optimized for the high-strength Nylon membrane, which is ideal for clarifying basic and neutral mobile phases
• Chemical Filtration - Excellent resistance to esters, bases, and alcohols makes Nylon the go-to choice for composite chemical streams
• Dissolution Testing - Nylon is the industry standard for automating dissolution workflows due to its broad solvent compatibility
• Analytical Sample Prep - Optimized to ensure data integrity by effectively removing particulates before instrumental analysis
• Environmental Monitoring - Ideal for removing particulates in water and wastewater analysis to ensure regulatory compliance
• General Laboratory Filtration - Increases workflow efficiency by protecting analytical instruments without sacrificing flow rates