Whatman
Pura Disc 25mm Nylon Syringe Filters, 0.45um, 1000 Pk SKU: 6753-2504

Nylon (NY) Syringe Filters, 0.45µm, 25mm - 6753-2504

Reducing background noise in analytical assays begins with proper clarification, and the Nylon Whatman Puradisc, 25mm, Syringe Filter, 0.45µm 1000/pk is engineered to remove interfering solids efficiently. To ensure analytical precision, the unit is constructed with a high-grade Nylon membrane providing a consistent 0.45 cutoff that passes only your target analyte. Encasing this critical media is a high-purity polypropylene housing that prevents sample bypass and ensures that every microliter is processed with high fidelity. Ultimately, this rigorous attention to manufacturing quality ensures batch-to-batch reproducibility, allowing laboratories to standardize their workflows with total confidence.

Key Nylon Membrane Characteristics

• Nylon membrane with hydrophilic affinity
• High Protein Binding characteristics
• Compatible with aqueous (non-acidic) solutions and most organic solvents
• High binding matrix: Avoid use with biological samples where yield is critical; incompatible with acidic solutions (pH < 3)
• Verified 0.45 retention rating for clarification

Key Housing Characteristics

• High-purity Polypropylene encapsulation housing
• Luer-Lok/ Luer Slip for secure fitting
• 4.2cm² effective filtration area
• <100µl holdup volume to minimize sample loss

You can streamline your sample preparation process significantly by adopting a filtration solution designed to handle your specific volume requirements. Protecting your downstream processes requires a defensive strategy, and utilizing these verified filters gives you the peace of mind that your work is safe. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.0 bar (29 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wetability

Hydrophilic

• Dissolution Testing - Nylon is the industry standard for automating dissolution workflows due to its broad solvent compatibility
• HPLC Sample Preparation - Optimized for the high-strength Nylon membrane, which is ideal for clarifying basic and neutral mobile phases
• Chemical Filtration - Excellent resistance to esters, bases, and alcohols makes Nylon the go-to choice for composite chemical streams
• Research & Development - Supports protocols that need to remove particulates, providing the ability to protect analytical instruments
• Analytical Sample Prep - Optimized to ensure data integrity by effectively removing particulates before instrumental analysis
• Quality Control Testing - Optimized for delivering reproducible results by removing particulates in standard pharmaceutical protocols