Pura Disc 25mm Nylon Syringe Filters, 0.45um, 1000 Pk
Whatman SKU: 6753-2504

Whatman Puradisc Nylon Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 6753-2504

Whatman manufactures under Cytiva's quality infrastructure, drawing on a filtration heritage that spans laboratory, environmental, and industrial applications. At the point of sample preparation, a syringe filter removes particulates before the sample reaches the instrument. Nylon delivers sharp particle cutoff at the rated pore size while drawing aqueous samples through without a pre-wetting step and resists particle shedding through extended cycles. The polypropylene housing holds a reliable seal against the membrane edge and keeps the fluid path low in extractable contamination. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• Low extractable contribution to sensitive analytical preparations
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• High tensile strength for stability under elevated differential pressures
• Non-sterile for routine clarification and sample prep

Housing Specifications

• Low extractable contribution protects sensitive downstream analyses
• Optimized internal geometry minimizes backpressure in service
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Medical-grade polypropylene with broad chemical compatibility

Reproducible separations start with samples that reach the column free of particulates. Upstream sample clarification keeps your separations clean and reproducible from sample preparation through final injection. Ask the Tisch Scientific team about blanket-order pricing and quality documentation for your routine filtration needs.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.0 bar (29 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Nylon

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Dissolution Testing - Nylon is the industry standard for automating dissolution workflows due to its broad solvent compatibility
• HPLC Sample Preparation - Optimized for the high-strength Nylon membrane, which is ideal for clarifying basic and neutral mobile phases
• Chemical Filtration - Excellent resistance to esters, bases, and alcohols makes Nylon the go-to choice for composite chemical streams
• Research & Development - Supports protocols that need to remove particulates, providing the ability to protect analytical instruments
• Analytical Sample Prep - Optimized to ensure data integrity by effectively removing particulates before instrumental analysis
• Quality Control Testing - Optimized for delivering reproducible results by removing particulates in standard pharmaceutical protocols