Pura Disc 4 mm PVDF Syringe Filters, 0.45um, 100/Pk
Whatman SKU: 6779-0404

Whatman Puradisc PVDF Syringe Filters, 0.45 µm, 4 mm, 100/Pk - 6779-0404

Whatman verifies performance ratings at the lot level using process controls that stay uniform across its entire filtration lineup. Because each syringe filter is dedicated to one sample, a failed or contaminated filtration never delays the next analyst's run waiting on a shared holder. Hydrophilic PVDF suits HPLC sample preparation with immediate, reliable uptake while enforcing absolute cutoff at its micron rating and keeps HPLC analytes from adhering to the pore surface. The polypropylene housing presses snugly against the membrane during the pass while routing flow to minimize backpressure in service and resists degradation from routine sample matrices. Where small-volume samples must reach the instrument clean, low hold-up volume keeps sample loss minimal while the instrument stays protected from particulate damage.

Membrane Characteristics

• Ethylene oxide sterilization cycles leave pore integrity and flow performance intact
• Chemical compatibility spans the full pH 1 to 14 range
• Hydrochloric, dilute nitric, and up to 90% sulfuric acid cause no attack
• Resistance to hydrolytic degradation exceeds that of nylon membranes
• Aqueous and HPLC samples wet the surface without pre-wetting

Housing Characteristics

• Minimal intrinsic autofluorescence from the polypropylene housing supports background-sensitive fluorescence-based assay work downstream.
• Low moisture absorption keeps the housing dimensionally stable through humid storage and shipping
• Impact-tolerant polypropylene body withstands routine bench handling without damage
• Plasticizer-free polyolefin construction keeps the fluid path clean

Filtering buffers, reagents, and aqueous samples keeps your preparation moving and consistent. Consistent aqueous clarification clears particulates without slowing your bench routine across the buffers and reagents your day-to-day prep depends on. Request Whatman's lot documentation and performance history to support your protocol validation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

4mm

Filtration Area

0.2cm²

Holdup Volume

<10µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

100°C

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 2ml

Wettability

Hydrophobic

• Spectroscopy Prep - Provides optical clarity and low background interference, ideal for UV-Vis and fluorescence sample preparation work.
• Forensic Toxicology Screening - Clarifies urine samples ahead of LC-MS drug screening, supporting reliable detection of abused drugs and metabolites.
• IC Guard Filtration - Removes particulates from aqueous samples before ion analysis, keeping detector cells free of fouling between injections.
• Capillary Electrophoresis Prep - Clarifies CE sample buffers and matrices, supporting stable electropherogram baselines for accurate results.
• Mycotoxin Screening - Clarifies grain and food extracts ahead of HPLC analysis, supporting reliable detection of aflatoxins and other mycotoxins.
• Beverage QC - Clarifies wine, beer, and juice samples ahead of HPLC testing for organic acids, sugars, and preservatives.