Pura Disc 4 mm PTFE Syringe Filters, 0.45um, 500 Pk
Whatman SKU: 6783-0404

Whatman Puradisc PTFE Syringe Filters, 0.45 µm, 4 mm, 500/Pk - 6783-0404

Whatman's filtration expertise, refined across a century-plus of disciplined manufacturing, has made its name synonymous with laboratory-grade quality worldwide. A syringe filter dispenses filtrate directly into an autosampler vial, without the intermediate collection vessel a bulk vacuum filtration setup typically needs. The PTFE membrane withstands aggressive organics that degrade other media and filters aggressive organic solvents without breakdown. Polypropylene construction resists chemical degradation from routine sample matrices while sustaining efficient flow on viscous samples and presses snugly against the membrane during the pass. When chromatographic methods demand particle-free injections, the column stays clean from run to run, protecting method performance and column life.

Technical Specifications

• Non-wetting pore surface blocks liquid water while passing water vapor freely
• Non-fibrous, fully synthetic structure sheds no fibers into filtrate
• Biological inertness resists enzymatic attack from proteases and lipases
• Low non-specific protein binding preserves recovery of biomolecules and therapeutic proteins during filtration
• Water contact angle near 120 degrees marks strong hydrophobicity

Housing Specifications

• Minimal ionic background from the polypropylene housing supports ion chromatography and trace-metal ICP-MS sample preparation.
• Standardized luer connection geometry provides secure engagement with standard syringe tips
• Rigid polypropylene body maintains its geometry through routine filtration pressure
• Plasticizer-free polyolefin construction keeps the fluid path clean

Handling the harsh solvents your methods demand means choosing a filter built to withstand what passes through it, run after run. Reliable solvent prefiltration clears particulates from your organic samples so your downstream method starts with a clean sample. Ask about Whatman's quality documentation to confirm your filtration step meets a recognized laboratory-science standard.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

0.6 bar (9 psi) [IPA]

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

4mm

Filtration Area

0.2cm²

Holdup Volume

<10µl

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

100°C

Pack Count

500

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 2ml

Wettability

Hydrophobic

• Chemical Synthesis - Resists aggressive organic solvents and corrosive acids for compatibility with harsh synthetic reaction mixtures.
• UV Spectroscopy - Clarifies solvent-based samples before UV/Vis analysis, removing scattering particulates for precise, reliable absorbance readings.
• Battery Electrolyte Prep - Clarifies lithium-ion battery electrolyte in carbonate solvents ahead of GC-MS purity and impurity analysis.
• Spirits Congener Analysis - Clarifies distilled spirits samples ahead of GC analysis, protecting columns from residue during congener profiling.
• Toxicology Screening - Clarifies protein-precipitated serum, plasma, and urine extracts ahead of LC-MS or GC-MS drug screening analysis.
• Dissolution Testing - Stops the dissolution reaction and clarifies samples, with low API binding for accurate potency quantitation.