Pura Disc 25mm PTFE Syringe Filters, 0.45um, 200 Pk
Whatman SKU: 6785-2504

Whatman Puradisc PTFE Syringe Filters, 0.45 µm, 25 mm, 200/Pk - 6785-2504

Whatman has built such a strong track record in published methods that laboratories default to citing its name in standardized protocols. Sample preparation for chromatography often ends with a syringe filter on the path to the vial. The PTFE matrix handles concentrated acids and bases across demanding methods while staying chemically inert against solvents, acids, and alkalis in service and excludes particles larger than the declared micron limit. The polypropylene housing keeps the sample chemically unaltered across the pass and stays inert across common laboratory solvents. When chromatographic methods demand particle-free injections, point-of-use syringe filtration clarifies the sample before it reaches the column.

Technical Specifications

• PTFE retains flexibility without embrittlement down to -73°C, allowing filtration of samples taken directly from cold-chain or freeze-thaw storage.
• Hydrophobic PTFE's non-wetting pore surface blocks liquid water by surface tension while passing water vapor freely, the same interfacial mechanism exploited in membrane distillation water treatment.
• Low extractables keep the chromatographic background clean
• PTFE resists hydrofluoric acid, clearing particulate from acid-digested samples ahead of ICP-MS and ICP-OES trace metals analysis.
• PTFE carries a UL 94 V-0 flammability rating, the highest self-extinguishing classification for polymer materials

Housing Specifications

• Plasticizer-free polyolefin construction keeps the fluid path clean
• Stable across the full aqueous pH range in routine sample work
• Translucent housing wall allows visual confirmation of sample flow during filtration
• Standardized luer taper geometry provides secure engagement with standard syringe tips

Filtering aggressive solvents and reagents through a filter that holds up to the chemistry keeps your sample prep reliable. Reliable solvent prefiltration clears particulates from your organic samples before it moves on to your next process step. Bulk pricing kicks in on larger filtration orders, so ask the Tisch Scientific team for a quote.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

0.6 bar (9 psi) [IPA]

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Flow Rate

~30 (MeOH)

Holdup Volume

<100µl

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

200

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Agrochemical Formulation QC - Clarifies technical pesticide concentrates in organic solvent ahead of HPLC potency and impurity analysis.
• Battery Electrolyte Prep - Clarifies lithium-ion battery electrolyte in carbonate solvents ahead of GC-MS purity and impurity analysis.
• Dissolution Testing - Stops the dissolution reaction and clarifies samples, with low API binding for accurate potency quantitation.
• Photoresist Filtration - Clarifies photoresist solutions in organic casting solvent ahead of spin-coating, reducing particulate defect risk.
• UV Spectroscopy - Clarifies solvent-based samples before UV/Vis analysis, removing scattering particulates for precise, reliable absorbance readings.
• Spirits Congener Analysis - Clarifies distilled spirits samples ahead of GC analysis, protecting columns from residue during congener profiling.