Pura Disc 13mm PVDF Syringe Filters, 0.45um, 500 Pk
Whatman SKU: 6792-1304

Whatman Puradisc PVDF Syringe Filters, 0.45 µm, 13 mm, 500/Pk - 6792-1304

Whatman draws on Cytiva's broader manufacturing oversight while continuing a legacy of filtration work that touches laboratory research, environmental monitoring, and industrial processing alike. Across analytical workflows, the syringe filter is where particulates leave the sample stream. The surface modification reverses PVDF's natural affinity for protein adsorption and suits HPLC sample preparation with immediate, reliable uptake. The PP housing sustains efficient flow on viscous samples while leaving no seam for sample to bypass the membrane and sheds virtually no extractable material into the sample. For routine sample preparation across many methods, the syringe filter folds clarification into one disposable step.

Technical Specifications

• Broad chemical compatibility gives PVDF membrane a working pH range of 1 to 14 in aqueous solutions
• PVDF's cast membrane structure releases no fibers into the filtrate, unlike depth-media prefilters
• PVDF membrane withstands vapor-phase hydrogen peroxide decontamination cycles used in aseptic isolator and RABS processing
• PVDF membrane structure maintains integrity from -35 to 160°C
• Immediate aliquot filtration in USP General Chapter 711 dissolution testing halts further API dissolution, preventing time-dependent potency bias

Housing Specifications

• Minimal extractable release from the housing supports sensitive analytical work downstream
• Impact-tolerant polypropylene body withstands routine bench handling without damage
• Withstands ethylene oxide gas sterilization without embrittlement or structural damage.
• Stable across the full aqueous pH range in routine sample work

Clarify your routine aqueous samples in a single pass and cut down on juggling multiple filter types at the bench. Consistent aqueous clarification clears particulates without slowing your bench routine the same way every time you run it. Request Whatman's lot documentation and performance history to support your protocol validation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

1.2 bar (17 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

13mm

Filtration Area

1.3cm²

Holdup Volume

<25µl

Material

Polyvinylidene Difluoride (PVDF)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

500

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 10ml

Wettability

Hydrophobic

• Pre-Blot Sample Prep - Ensures ultra-low protein binding for maximum sample recovery ahead of sensitive immunodetection protocols and assays.
• LC-MS Sample Prep - Delivers low-extractable filtrates that prevent ion suppression, supporting clean baselines for LC-MS analysis.
• Water Quality Monitoring - Clarifies environmental and drinking water samples ahead of turbidity, ion, or contaminant testing in monitoring programs.
• HPLC Prep - Delivers high flow rates for mild organic HPLC mobile phases, ensuring clean baselines and protecting analytical columns.
• Capillary Electrophoresis Prep - Clarifies CE sample buffers and matrices, supporting stable electropherogram baselines for accurate results.
• Dissolution Testing - Removes undissolved particles from timed USP 711 dissolution aliquots, preventing skewed potency and release results.