Pura Disc 25mm PES Syringe Filters, 0.45um, 1000 Pk
Whatman SKU: 6794-2504

Whatman Puradisc Polyethersulfone (PES) Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 6794-2504

Whatman verifies performance ratings at the lot level using process controls that stay uniform across its entire filtration lineup. Sample preparation for chromatography often ends with a syringe filter on the path to the vial. The PES membrane clarifies particulates at the rated pore size while needing a surface treatment before its polysulfone base wets and keeps that modified surface active throughout use. The polypropylene housing resists aqueous acids, bases, and alcohols in routine use and maintains structural integrity through elevated-temperature sample preparation. When chromatographic methods demand particle-free injections, the column stays clean from run to run, protecting method performance and column life.

Technical Specifications

• Mechanical strength keeps the matrix intact under vacuum or pressure
• Absolute pore size rating holds consistent across every lot
• Compatibility spans both nucleic acid and protein-based filtration
• Operating temperatures up to 130°C leave mechanical integrity intact
• PFAS extractables test non-detectable under EPA Method 537.1

Housing Specifications

• The seal formed against the membrane blocks bypass at rated operating pressure
• Housing retains dimensional stability and seal integrity through elevated-temperature operation up to 121°C.
• Burst pressure rating provides a wide safety margin above the rated maximum operating pressure.
• Standardized luer connection geometry provides secure engagement with standard syringe tips

Clarify your routine aqueous samples in a single pass and cut down on juggling multiple filter types at the bench. Consistent aqueous clarification clears particulates without slowing your bench routine across the buffers and reagents your day-to-day prep depends on. Ask our team about Whatman's performance credentials before you commit to a filtration standard requiring documented quality.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

2.3 bar (33 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Biological Assays - Protects sensitive enzymatic and antibody-based assays from particulate interference without adsorbing critical reagents.
• Urine Drug Screening - Clarifies protein-poor urine samples for dilute-and-shoot LC-MS/MS toxicology testing without adsorbing target drug analytes.
• Life Science Prep - Speeds processing of viscous biological solutions, improving laboratory workflow efficiency during busy sample prep days.
• Sample Recovery - Minimizes sample loss in low-protein-binding applications, delivering high yield for precious or rare biological specimens.
• Serum Filtration - Clarifies serum and plasma samples quickly while retaining critical proteins needed for accurate downstream analytical testing.
• Biological Fluids - Filters buffers and biological fluids efficiently, using the PES membrane to maximize flow and minimize non-specific binding.