Pura Disc 25mm PES Syringe Filters, 0.2um, 1000 Pk
Whatman SKU: 6794-2512

Whatman Puradisc Polyethersulfone (PES) Syringe Filters, 0.2 µm, 25 mm, 1000/Pk - 6794-2512

Whatman has built such a strong track record in published methods that laboratories default to citing its name in standardized protocols. Sterilizing-grade syringe filters deliver sterile-grade retention as a single-use format, eliminating the autoclaving and cleaning cycle a reusable sterile filtration setup would require. PES's open pore layout leaves proteins less surface to contact while trapping bacteria reliably at its sterilizing-grade pore rating and tolerates aliphatic alcohols, glycols, and aqueous buffers. Polypropylene construction maintains a low-dead-volume internal flow path while resisting degradation from routine sample matrices and holds its geometry through sample filtration at temperatures up to 121°C. Where bacterial contamination must stay out of the sample, manufacturer-tested retention keeps the instrument and downstream assay protected without a housing to maintain or clean.

Technical Specifications

• Pore structure integrity holds through autoclave cycles up to 126°C
• Absolute pore size rating holds consistent across every lot
• Aromatic sulfone backbone underlies stability across the full pH range
• DNA and RNA pass through with negligible adsorptive loss
• Non-ionic surface avoids charge-driven protein binding of positively and negatively charged membrane types

Housing Specifications

• Optimized internal geometry minimizes backpressure in service
• Minimal extractable release from the housing supports sensitive analytical work downstream
• PP housing rated to 121°C holds its geometry through high-temperature sample preparation and processing.
• Plasticizer-free polyolefin construction keeps the fluid path clean

A clean particulate separation keeps your aqueous sample preparation dependable. General-purpose aqueous filtration supports the sample types you handle every day from reagent and buffer preparation through routine sample clarification. Standardize your filtration purchases across every method with volume pricing and documentation from the Tisch Scientific team.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

3.4 bar (50 psi)

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Holdup Volume

<100µl

Material

Polyethersulfone (PES)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.2

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophilic

• Organic Carbon Testing - Clarifies water samples ahead of DOC and UV254 analysis while keeping organic carbon adsorption to the membrane minimal.
• Urine Drug Screening - Clarifies protein-poor urine samples for dilute-and-shoot LC-MS/MS toxicology testing without adsorbing target drug analytes.
• Sample Recovery - Minimizes sample loss in low-protein-binding applications, delivering high yield for precious or rare biological specimens.
• Media Preparation - Facilitates rapid sterilization of tissue culture additives, lowering contamination risk during sensitive laboratory work.
• Pesticide Residue Testing - PES membranes improve polar pesticide recovery in food-safety LC-MS/MS testing versus hydrogen-bonding nylon.
• PFAS Water Testing - PES filters process aqueous samples for EPA Method 1633A PFAS testing without added fluorinated background.