Pura Disc 25mm PTFE Syringe Filters, 0.45um, 1000 Pk
Whatman SKU: 6798-2504

Whatman Puradisc PTFE Syringe Filters, 0.45 µm, 25 mm, 1000/Pk - 6798-2504

Whatman draws on Cytiva's broader manufacturing oversight while continuing a legacy of filtration work that touches laboratory research, environmental monitoring, and industrial processing alike. A syringe filter's small hold-up volume limits sample loss, a meaningful difference when working with a limited or precious sample. Chemically inert PTFE resists attack from the harshest process chemistries while filtering aggressive organic solvents without breakdown and reaches the same absolute retention on every run. The polypropylene housing routes flow to minimize backpressure in service while standing firm against aqueous acids, bases, and alcohols during regular handling and holds its seal true run after run. Where small-volume samples must reach the instrument clean, low hold-up volume keeps sample loss minimal while the instrument stays protected from particulate damage.

Technical Specifications

• Gas-venting and liquid-blocking function survives repeated autoclave sterilization cycles
• Low non-specific protein binding preserves recovery of biomolecules and therapeutic proteins during filtration
• Non-fibrous, fully synthetic structure sheds no fibers into filtrate
• Insolubility in all known organic solvents avoids swelling and pore distortion
• Chemical resistance spans the full pH 1 to 14 range

Housing Specifications

• Low moisture absorption keeps the housing dimensionally stable through humid storage and shipping
• Thermal-bonded construction keeps adhesives out of the fluid path
• Minimal extractable release from the housing supports sensitive analytical work downstream
• Dilute aqueous acids, bases, and alcohols used in sample prep do not degrade the polypropylene housing

Removing particulates from organic solvents and reagents before they move downstream keeps contamination out of your results. Reliable solvent prefiltration clears particulates from your organic samples so your downstream method starts with a clean sample. Ask about Whatman's quality documentation to confirm your filtration step meets a recognized laboratory-science standard.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

0.6 bar (9 psi) [IPA]

Burst Pressure (psi)

75psi

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene

Diameter

25mm

Filtration Area

4.2cm²

Flow Rate

~30 (MeOH)

Holdup Volume

<100µl

Material

Polytetrafluoroethylene (PTFE)

Maximum Operating Pressure

75psi

Maximum Operating Temperature (°C)

121°C

Pack Count

1000

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable 121°C

Volume Throughput (ml)

Up to 100ml

Wettability

Hydrophobic

• Polymer GPC Prep - Clarifies polymer solutions in THF ahead of gel permeation chromatography, protecting columns from particulates.
• UV Spectroscopy - Clarifies solvent-based samples before UV/Vis analysis, removing scattering particulates for precise, reliable absorbance readings.
• Water Monitoring - After alcohol pre-wet, PTFE's chemical inertness holds up through repeated environmental sample runs without degrading.
• Spirits Congener Analysis - Clarifies distilled spirits samples ahead of GC analysis, protecting columns from residue during congener profiling.
• Venting Applications - Protects vacuum pumps and vents bioreactors using a hydrophobic PTFE membrane that forms a reliable air barrier.
• Photoresist Filtration - Clarifies photoresist solutions in organic casting solvent ahead of spin-coating, reducing particulate defect risk.