Autovial 12 Syringeless Filter, Glass PreFilter, 0.45um, PVDF Filteration Medium, 50 pcs
Whatman SKU: AV125UAQU

PVDF Syringeless Filters - AV125UAQU

By removing the separate filter and syringe from sample preparation, syringeless filters reduce setup time and limit the particulate carryover that can raise autosampler backpressure and shorten column life. PVDF holds up to alcohols and mild hydrocarbon solvents while delivering absolute particle cutoff at the rated pore size and suits HPLC sample preparation and aqueous clarification. Polypropylene construction resists chemical degradation from routine sample matrices and holds extractables low for sensitive analyses. Cleaner, more uniform injections follow, giving the method the reproducibility that quantitative analysis depends on.

Technical Specifications

• Thin membrane structure sustains high flow for fast sample throughput
• Ultra-low protein binding preserves dilute analytes for maximum recovery
• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Absolute pore size rating gives consistent results across protocols
• Low extractables preserve a clean chromatographic baseline

Housing Specifications

• Optimized internal geometry minimizes backpressure in service
• Reliable housing-to-membrane seal prevents bypass at rated pressure
• Thermal-bonded construction keeps adhesives out of the fluid path
• Resists aqueous acids, bases, and alcohols in routine sample prep

Upstream clarification pays for itself by keeping your columns clear and your analytical day on schedule. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Ask our friendly customer service team to confirm the cap size, septa material, and thread your method requires.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Construction

Polypropylene (PP)

Material

Polyvinylidene Fluoride (PVDF)

Pore Size (µm)

0.45

Sterility

Sterile

Wettability

Hydrophilic

• Solubility Assay Filtration - Positive-pressure filtration cleanly clarifies small sample volumes, supporting accurate solubility determination.
• Protein Precipitation Cleanup - Low protein binding retains analyte integrity when filtering precipitated sample supernatants.
• Direct Sample Filtration - Built-in membrane clarifies the sample in one manual step, cutting transfer steps before chromatographic injection.
• HPLC Sample Prep - Plunger-driven filtration removes particulates from analytical samples, protecting columns from clogging and back pressure.
• Pharmaceutical QC Testing - Content uniformity and dissolution samples are clarified in one step, reducing handling before chromatographic injection.
• Heavy Particulate Samples - Glass microfiber prefilter traps large debris through its fibrous depth, preventing premature membrane blockage.