Autovial 12 Syringeless Filter, Glass PreFilter, 0.45um, Nylon Filteration Medium, 50 pcs
Whatman SKU: AV125UNAO

Nylon Syringeless Filters - AV125UNAO

By removing the separate filter and syringe from sample preparation, syringeless filters reduce setup time and limit the particulate carryover that can raise autosampler backpressure and shorten column life. Nylon delivers sharp particle cutoff at the rated pore size and adds a layered prefilter for particulate-laden samples. The polypropylene housing holds a reliable seal against the membrane edge while maintaining a low-dead-volume internal flow path and contributes minimal extractables to the filtrate. Where high-throughput HPLC and UHPLC demand consistent injections, that uniformity keeps method performance predictable.

Technical Specifications

• Low extractable contribution to sensitive analytical preparations
• Absolute pore size rating provides consistent results across filtration protocols
• Layered prefiltration sustains flow through turbid, particulate-laden samples
• Alkaline-resistant across a broad range of aqueous buffers
• Stable across the pH 3 to 12 operating range

Housing Specifications

• Thermal-bonded construction keeps adhesives out of the fluid path
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Medical-grade polypropylene with broad chemical compatibility
• Optimized internal geometry minimizes backpressure in service

Sample clarification before injection is the cheapest insurance your chromatography system has. Pre-injection filtration protects the resolution your methods depend on so your retention times and peak shapes stay consistent. Connect with our customer support technicians to standardize vials, caps, and septa across your chromatography workflows.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Construction

Polypropylene (PP)

Material

Nylon

Pore Size (µm)

0.45

Sterility

Nonsterile

Wettability

Hydrophilic

• Direct Sample Filtration - Built-in membrane clarifies the sample in one manual step, cutting transfer steps before chromatographic injection.
• Tissue Culture Media Prep - A glass-fiber prefilter and downstream membrane remove cellular debris from culture media before injection.
• Solubility Assay Filtration - Positive-pressure filtration cleanly clarifies small sample volumes, supporting accurate solubility determination.
• Pharmaceutical QC Testing - Content uniformity and dissolution samples are clarified in one step, reducing handling before chromatographic injection.
• Heavy Particulate Samples - Glass microfiber prefilter traps large debris through its fibrous depth, preventing premature membrane blockage.
• Column Lifetime Extension - Consistent sub-micron particle removal before injection reduces column contamination and back pressure buildup.