Autovial 12 Syringeless Filter, Glass PreFilter, 0.45um, PVDF Filteration Medium, 1000 pcs
Whatman SKU: AV525UAQU

PVDF Syringeless Filters - AV525UAQU

Across UniPrep, Mini-UniPrep, and Autovial formats, syringeless filters integrate filtration into one disposable, so analysts clarify a sample without assembling and changing filters between runs. Hydrophilic PVDF suits HPLC sample preparation and aqueous clarification while keeping analyte adsorption low for clean recovery and delivers absolute particle cutoff at the rated pore size. The polypropylene housing resists aqueous acids, bases, and alcohols and sustains efficient flow on viscous samples. Where high-throughput HPLC and UHPLC demand consistent injections, that uniformity keeps method performance predictable.

Technical Specifications

• Hydrophilic surface wets aqueous and HPLC samples without pre-wetting
• Resists HPLC mobile phases, alcohols, and mild hydrocarbons
• Absolute pore size rating gives consistent results across protocols
• Thin membrane structure sustains high flow for fast sample throughput
• Ultra-low protein binding preserves dilute analytes for maximum recovery

Housing Specifications

• Low extractable contribution protects sensitive downstream analyses
• Thermal-bonded construction keeps adhesives out of the fluid path
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Optimized internal geometry minimizes backpressure in service

Sample clarification before injection is the cheapest insurance your chromatography system has. Pre-injection filtration protects the resolution your methods depend on across reversed-phase and normal-phase workflows. Ask our friendly customer service team to confirm the cap size, septa material, and thread your method requires.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Construction

Polypropylene (PP)

Material

Polyvinylidene Fluoride (PVDF)

Pore Size (µm)

0.45

Sterility

Nonsterile

Wettability

Hydrophilic

• High-Throughput Prep - Disposable single-unit format speeds batch sample preparation by eliminating syringe assembly and cleanup between samples.
• Heavy Particulate Samples - Glass microfiber prefilter traps large debris through its fibrous depth, preventing premature membrane blockage.
• Bioanalytical Sample Cleanup - Low-binding membranes clarify plasma and serum extracts, retaining drug analytes for accurate quantitation.
• Direct Sample Filtration - Built-in membrane clarifies the sample in one manual step, cutting transfer steps before chromatographic injection.
• Column Lifetime Extension - Consistent sub-micron particle removal before injection reduces column contamination and back pressure buildup.
• Solubility Assay Filtration - Positive-pressure filtration cleanly clarifies small sample volumes, supporting accurate solubility determination.