Autovial 12 Syringeless Filter, Glass PreFilter, 0.45um, Nylon Filteration Medium, 1000 pcs
Whatman SKU: AV525UNAO

Nylon Syringeless Filters - AV525UNAO

By removing the separate filter and syringe from sample preparation, syringeless filters reduce setup time and limit the particulate carryover that can raise autosampler backpressure and shorten column life. The nylon membrane resists alkaline conditions across a broad buffer range while pairing with an integrated glass-fiber prefilter for turbid samples and withstands elevated differential pressures. The polypropylene housing holds a reliable seal against the membrane edge and maintains a low-dead-volume internal flow path. Standardized this way, sample preparation becomes one of the most controlled and repeatable steps in the analytical workflow.

Technical Specifications

• High tensile strength for stability under elevated differential pressures
• Alkaline-resistant across a broad range of aqueous buffers
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Layered prefiltration sustains flow through turbid, particulate-laden samples

Housing Specifications

• Medical-grade polypropylene with broad chemical compatibility
• Optimized internal geometry minimizes backpressure in service
• Resists aqueous acids, bases, and alcohols in routine sample prep
• Thermal-bonded construction keeps adhesives out of the fluid path

Upstream clarification pays for itself by keeping your columns clear and your analytical day on schedule. Upstream sample clarification keeps your separations clean and reproducible from sample preparation through final injection. Ask our friendly customer service team to confirm the cap size, septa material, and thread your method requires.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Construction

Polypropylene (PP)

Material

Nylon

Pore Size (µm)

0.45

Sterility

Nonsterile

Wettability

Hydrophilic

• Pharmaceutical QC Testing - Content uniformity and dissolution samples are clarified in one step, reducing handling before chromatographic injection.
• Tissue Culture Media Prep - A glass-fiber prefilter and downstream membrane remove cellular debris from culture media before injection.
• High-Throughput Prep - Disposable single-unit format speeds batch sample preparation by eliminating syringe assembly and cleanup between samples.
• Heavy Particulate Samples - Glass microfiber prefilter traps large debris through its fibrous depth, preventing premature membrane blockage.
• Direct Sample Filtration - Built-in membrane clarifies the sample in one manual step, cutting transfer steps before chromatographic injection.
• Light-Sensitive Samples - Amber housing options shield photosensitive analytes from light during filtration for chromatographic preparation.