CA Membrane Circle (OE 67), 0.45um Pore Size, 142mm Circle (25 pcs) SKU: 10404031

Cellulose Acetate (CA) Membrane Filters - 10404031

The Whatman 10404031 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Manufactured to exacting specifications, a uniform Cellulose Acetate (CA) matrix maintains its rated 0.45 cutoff under the pressures and flow conditions encountered during routine laboratory filtration. To this end, precision manufacturing ensures that each membrane disc delivers the rated retention, flow rate, and surface consistency that analytical and microbiological methods require.

Material Specifications

• Distinguished by their very low protein binding, making them ideal for protein recovery.
• Bulk format reduces per-unit packaging waste and cost, appropriate for routine particulate removal and clarification where aseptic handling is not specified.
• Manufactured with a uniform pore structure that maintains consistent retention characteristics across the full membrane surface.
• Particularly well suited for electrophoresis and immunoassay support applications where predictable binding behavior is essential.
• Offer improved chemical resistance to low molecular weight alcohols compared to MCE.

Maintaining accreditation under ISO 17025 or similar quality frameworks requires documented traceability at every step — the specification compliance of each membrane lot supports your ongoing audit readiness. In response, CA membranes provide a naturally hydrophilic surface that wets immediately with aqueous solutions, eliminating pre-treatment steps and reducing the hands-on time in your sample preparation protocol. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

35.0psi

Color

white

Diameter

142mm

Extractables

low

Filtration Area

158.37cm²

Flow Rate

55ml (Water)

Grid (Yes/No)

No

Material

Cellulose Acetate (CA)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

180°C

Membrane Thickness (µm)

135um

Pack Count

25

pH Range

4-8

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Biological Fluid Prep - Clarifies urine or cerebrospinal fluid for clinical chemistry without removing the low-abundance proteins of interest.
• Low Binding Filtration - Ideal for filtering dilute protein solutions where maximum recovery is needed to maintain experimental accuracy.
• Wine Stability Testing - Filters wine samples to check for colloidal stability, ensuring the product will not precipitate during shelf storage.
• Isotope Studies - Used in binding studies where the membrane itself must not interact with the radioactive ligand or the receptor protein.
• Enzyme Sterilization - Preserves enzymatic activity during cold sterilization, preventing the denaturation often caused by surface binding.
• Groundwater Filtration - Filters dissolved metals samples without adsorption, ensuring the filtrate represents the true environmental state.