CA Membrane Circle (OE 67), 0.45um Pore Size, 85mm Circle (50 pcs) SKU: 10404044

Cellulose Acetate (CA) Membrane Filters - 10404044

The Whatman 10404044 combines a controlled pore size distribution with low extractable levels, ensuring the data accuracy that sensitive analytical methods require. At its core, precision membrane geometry balances retention sharpness with sustainable flow rates, minimizing the pressure buildup that leads to premature filter replacement. Taken together, from raw polymer through final inspection, the manufacturing process is designed to ensure that every membrane disc meets the performance specifications of its grade designation.

Material Specifications

• Packaged without sterilization for applications where downstream sterility is achieved by other means or is not a process requirement.
• Particularly well suited for electrophoresis and immunoassay support applications where predictable binding behavior is essential.
• Manufactured with a uniform pore structure that maintains consistent retention characteristics across the full membrane surface.
• Distinguished by their very low protein binding, making them ideal for protein recovery.
• Offer improved chemical resistance to low molecular weight alcohols compared to MCE.

Transitioning from qualitative screening to quantitative gravimetric analysis requires a membrane with documented tare weight consistency, and the manufacturing tolerances above ensure that your blank values remain within acceptable limits. The thermal tolerance of cellulose acetate allows autoclaving for applications where you need a sterilized membrane seated in your holder before introducing the sample, simplifying aseptic technique in your workflow. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

35.0psi

Color

white

Diameter

85mm

Extractables

low

Filtration Area

50.27cm²

Flow Rate

55ml (Water)

Grid (Yes/No)

No

Material

Cellulose Acetate (CA)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

180°C

Membrane Thickness (µm)

135um

Pack Count

50

pH Range

4-8

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Low Binding Filtration - Ideal for filtering dilute protein solutions where maximum recovery is needed to maintain experimental accuracy.
• Isotope Studies - Used in binding studies where the membrane itself must not interact with the radioactive ligand or the receptor protein.
• Nutrient Analysis - Clarifies water for nitrate/phosphate testing without leaching nitrogenous material that could bias the results.
• Tissue Culture Media - Sterilizes heat-labile media components with minimal hold-up volume, ensuring expensive additives are not wasted.
• Groundwater Filtration - Filters dissolved metals samples without adsorption, ensuring the filtrate represents the true environmental state.
• Enzyme Sterilization - Preserves enzymatic activity during cold sterilization, preventing the denaturation often caused by surface binding.