RC Membrane (RC58), 0.2um Pore Size, 47mm Circle (100 pcs) SKU: 10410312

Regenerated Cellulose (RC) Membrane Filters - 10410312

Engineered for high retention efficiency and superior chemical stability, the Whatman 10410312 achieves reliable separation results across a broad range of analytical and preparative applications. At its core, reproducible separation characteristics define the membrane structure, protecting downstream instruments and preserving sample integrity throughout the filtration process. Controlled production conditions produce membranes with documented pore size distribution and thickness tolerances, supporting method reproducibility across multiple filter lots.

Material Specifications

• Symmetric pore geometry provides predictable retention behavior across varying flow rates and pressure conditions.
• A premium choice for broad chemical compatibility without requiring pre-wetting.
• Minimal extractable levels make Regenerated Cellulose a reliable choice for analytical applications where background interference must be minimized.
• Regenerated Cellulose offers excellent chemical resistance to both aqueous and organic solvents.
• Mechanically stable and hydrophilic, often used for HPLC mobile phase degassing.

Multi-site studies where different laboratories must produce comparable data benefit from membranes manufactured to tight specifications, giving you confidence that site-to-site variability is not introduced by the filtration step. To address this, regenerated cellulose offers the lowest non-specific protein binding of any cellulose-based membrane, ensuring that your biological filtrates retain analyte concentrations close to the original sample without significant adsorptive loss. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40-65psi

Color

white

Diameter

47mm

Extractables

very low

Filtration Area

17.35cm²

Flow Rate

40ml (Water)

Grid (Yes/No)

No

Material

Regenerated Cellulose (RC)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

180°C

Membrane Thickness (µm)

160um

Pack Count

100

pH Range

3-12

Pore Size (µm)

0.2

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Particle Sizing - Used in automated particle counters to provide a clean, non-shedding background for accurate contaminant sizing data.
• Microplastic Collection - Filters water samples to capture microplastic fibers, providing a smooth background for microscopic categorization.
• Tissue Extract Clarification - Handles lipid-rich tissue extracts well, preventing the premature fouling often seen with hydrophobic membrane types.
• Dialysis Membrane Sheet - Used in custom dialyzers to facilitate buffer exchange and desalting of protein solutions via passive diffusion.
• Ultraclean Solvent Prep - Filters HPLC mobile phases with high efficiency, ensuring no extractables interfere with sensitive UV detection downstream.
• Multiplex Bead Assays - Retains microspheres in flow-through assays while allowing the sample matrix to wash away without trapping the beads.