Whatman
NC45 0.45um 25mm 100/Pk SKU: 10401106

Cellulose Nitrate (CN) Membrane Filters - 10401106

Engineered for high retention efficiency and superior chemical stability, the 10401106 achieves reliable separation results across a broad range of analytical and preparative applications. Verified 0.45 pore distribution across the Hydrophilic membrane surface guarantees batch-to-batch consistency in particle capture and analyte passage. Controlled production conditions produce membranes with documented pore size distribution and thickness tolerances, supporting method reproducibility across multiple filter lots.

Material Specifications

• Dissolves completely in specific organic solvents, enabling full recovery of captured particles from the membrane surface for downstream gravimetric, chemical, or spectroscopic analysis.
• Autoclavable at 121°C without loss of integrity, cellulose nitrate membranes maintain their rated pore structure and dimensional stability through repeated sterilization cycles.
• High protein binding capacity makes cellulose nitrate the preferred membrane for Western blotting, dot blotting, and nucleic acid immobilization techniques that rely on efficient surface adsorption.
• Naturally hydrophilic and compatible with aqueous solutions, cellulose nitrate delivers high flow rates and rapid wet-out without requiring pre-conditioning or surfactant treatment.
• Cellulose nitrate membranes feature a narrow pore size distribution and low extractable levels, providing the controlled retention characteristics required for gravimetric and particulate analysis.

Scaling your method from development to routine production requires membrane consistency at every lot — the documented specifications of these membranes provide the reproducibility needed to validate the filtration step once. The narrow pore size distribution of cellulose nitrate membranes ensures your retention data is consistent across batches, reducing the inter-sample variability that complicates quantitative particulate and microbiological analyses. For questions about chemical compatibility, operating limits, or equivalent product cross-references, Tisch Scientific's filtration specialists can provide the technical detail your method documentation requires.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Diameter

25mm

Pore Size (µm)

0.45

Sterility

Nonsterile

Wetability

Hydrophilic

• Microscopy mounting - Retains microorganisms on a flat surface, allowing for direct staining and enumeration under a high-power microscope.
• Stack Pre-filtration - Acts as a spacer or depth layer in multi-tier filtration stacks to extend the life of the final downstream membrane.
• Sediment Collection - Efficiently harvests precipitates from chemical reactions, allowing for the recovery and drying of the solid synthesis product.
• Quality Control Testing - Serves as a standard check filter for routine batch purity tests, verifying the absence of visible physical contaminants.
• Vacuum Clarification - Utilized in Buchner funnels to rapidly remove particulates from large-volume batches of non-critical laboratory buffers.
• Air Particulate Sampling - Traps airborne dust and pollen on a positioned open-face filter disc for subsequent microscopic or chemical analysis.