Whatman
NC45 0.45um 47mm 100/Pk SKU: 10401112

Cellulose Nitrate (CN) Membrane Filters - 10401112

Designed to deliver reproducibility and confidence across critical sample types, the 10401112 provides the filtration consistency that method validation demands. A uniform Cellulose Nitrate (CN) matrix maintains its rated 0.45 cutoff under the pressures and flow conditions encountered during routine laboratory filtration. From raw polymer through final inspection, the manufacturing process is designed to ensure that every membrane disc meets the performance specifications of its grade designation.

Material Specifications

• Dissolves completely in specific organic solvents, enabling full recovery of captured particles from the membrane surface for downstream gravimetric, chemical, or spectroscopic analysis.
• Cellulose nitrate membranes feature a narrow pore size distribution and low extractable levels, providing the controlled retention characteristics required for gravimetric and particulate analysis.
• Bulk packaging format provides cost-effective access for high-volume laboratories performing non-critical filtration and sample preparation.
• Maximum operating temperature of 80°C accommodates warm sample filtration and elevated-temperature processes that exceed the limits of standard devices.
• High protein binding capacity makes cellulose nitrate the preferred membrane for Western blotting, dot blotting, and nucleic acid immobilization techniques that rely on efficient surface adsorption.

Multi-site studies where different laboratories must produce comparable data benefit from membranes manufactured to tight specifications, giving you confidence that site-to-site variability is not introduced by the filtration step. Because cellulose nitrate dissolves completely in organic solvents like acetone and amyl acetate, you can recover every captured particle from the membrane surface for downstream gravimetric, spectroscopic, or chemical analysis. Sample quantities for method validation and compatibility testing are available through Tisch Scientific — request a sample to verify performance in your specific workflow before committing to a production volume.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Diameter

47mm

Pore Size (µm)

0.45

Sterility

Nonsterile

Wetability

Hydrophilic

• Quality Control Testing - Serves as a standard check filter for routine batch purity tests, verifying the absence of visible physical contaminants.
• Gravimetric Analysis - Captures total suspended solids from liquid samples on a weighed disc, ensuring accurate mass measurements for reporting.
• Sediment Collection - Efficiently harvests precipitates from chemical reactions, allowing for the recovery and drying of the solid synthesis product.
• Stack Pre-filtration - Acts as a spacer or depth layer in multi-tier filtration stacks to extend the life of the final downstream membrane.
• Microscopy mounting - Retains microorganisms on a flat surface, allowing for direct staining and enumeration under a high-power microscope.
• Radiometric Counting - Collects radioactive precipitates for scintillation counting, providing a consistent geometry for accurate data measurement.