MCE Circle ME Range (ME 25), Plain, 0.45um Pore Size, 90mm, 50Pk SKU: 10401618

Mixed Cellulose Ester (MCE) Membrane Filters - 10401618

Designed to deliver reproducibility and confidence across critical sample types, the Whatman 10401618 provides the filtration consistency that method validation demands. Constructed for reliable operation, a uniform Mixed Cellulose Ester (MCE) matrix maintains its rated 0.45 cutoff under the pressures and flow conditions encountered during routine laboratory filtration. In combination, each membrane disc reflects a manufacturing standard where retention characteristics, physical integrity, and dimensional accuracy are verified before release.

Material Specifications

• Hydrophilic by nature, the MCE membrane structure supports high non-specific adsorption for effective organism capture.
• Feature a uniform pore structure that provides consistent flow rates and high throughputs across the full range of standard pore size ratings.
• Mixed Cellulose Ester membranes combine cellulose acetate and cellulose nitrate polymers to deliver a smoother, more flexible membrane surface than pure cellulose nitrate.
• Bulk packaging format provides cost-effective access for high-volume laboratories performing non-critical filtration and sample preparation.
• The biologically inert blend of cellulose acetate and cellulose nitrate provides a membrane surface optimized for organism capture and colony enumeration in microbiological assays.

Scaling your method from development to routine production requires membrane consistency at every lot — the documented specifications of these membranes provide the reproducibility needed to validate the filtration step once. For this purpose, MCE's naturally hydrophilic surface allows immediate wetting upon contact with aqueous samples, eliminating the pre-conditioning step and letting you begin filtration as soon as the membrane is seated in your holder. Take control of your sample preparation variables and ensure that your data reflects the true nature of your work, rather than the quality of your consumables.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

35.0psi

Color

white

Diameter

90mm

Extractables

low

Filtration Area

63.62cm²

Flow Rate

60ml (Water)

Grid (Yes/No)

No

Material

Mixed Cellulose Esters (MCE)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

130°C

Membrane Thickness (µm)

135um

Pack Count

50

pH Range

4-8

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophilic

• Gravimetric Analysis - Maintains structural integrity during filtration and drying, providing precise weight measurements of retained particulates.
• Chemotaxis Assays - Acts as a barrier in Boyden chambers, allowing cells to migrate through defined pores towards a chemoattractant source.
• Water Quality Testing - Features a gridded surface for easy colony counting, essential for regulatory compliance in municipal water quality labs.
• Bioburden Monitoring - Routine testing of pharmaceutical water loops to ensure bioburden levels remain within safe production specifications.
• Yeast & Mold Monitoring - Optimized for the recovery of larger fungal organisms in beverage testing, providing a clear background for ID.
• Aqueous Filtration - Biologically inert composition provides high flow rates and consistent reliability for routine laboratory fluid processing.