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Thumbnail Filmstrip of MCE Circle ME Range (ME 25), White/Black Grid 3.1mm, 0.45um, 47mm, 100 /Pk Images
Mixed Cellulose Ester (MCE) Membrane Filters - 10406812
The Whatman 10406812 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Manufactured to exacting specifications, reproducible separation characteristics define the membrane structure, protecting downstream instruments and preserving sample integrity throughout the filtration process. In turn, lot-level verification of pore size, flow rate, and physical dimensions ensures that membrane performance remains predictable when scaling from method development to routine analysis.
Material Specifications
- The biologically inert blend of cellulose acetate and cellulose nitrate provides a membrane surface optimized for organism capture and colony enumeration in microbiological assays.
- Mixed Cellulose Ester membranes combine cellulose acetate and cellulose nitrate polymers to deliver a smoother, more flexible membrane surface than pure cellulose nitrate.
- Feature a uniform pore structure that provides consistent flow rates and high throughputs across the full range of standard pore size ratings.
- Low tare weight and complete solubility in organic solvents make MCE the standard membrane for gravimetric particulate analysis where method specifications demand minimal blank correction.
- Single-unit sterile packaging maintains aseptic integrity through storage and handling, supporting cleanroom protocols and GMP-compliant workflows.
Transitioning from qualitative screening to quantitative gravimetric analysis requires a membrane with documented tare weight consistency, and the manufacturing tolerances above ensure that your blank values remain within acceptable limits. In response, MCE's well-documented retention characteristics at standard pore ratings make it straightforward to specify in your method documentation, supporting the reproducibility and traceability that regulated workflows demand. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 40.6psi
- Color
- white
- Diameter
- 47mm
- Extractables
- low
- Filtration Area
- 17.35cm²
- Flow Rate
- 60ml (Water)
- Grid (Yes/No)
- Yes
- Material
- Mixed Cellulose Esters (MCE)
- Maximum Operating Pressure
- Holder-dependent
- Maximum Operating Temperature (°C)
- 130°C
- Membrane Thickness (µm)
- 145um
- Pack Count
- 100
- pH Range
- 4-8
- Pore Size (µm)
- 0.45
- Sterility
- Sterile
- Sterilization
- Supplied Sterile (Single Use)
- Support Material
- None
- Wettability
- Hydrophilic
- Biochemical Assays - High electrostatic properties effectively bind proteins and macromolecules, supporting various diagnostic and research assays.
- Gravimetric Analysis - Maintains structural integrity during filtration and drying, providing precise weight measurements of retained particulates.
- Bioburden Monitoring - Routine testing of pharmaceutical water loops to ensure bioburden levels remain within safe production specifications.
- Yeast & Mold Monitoring - Optimized for the recovery of larger fungal organisms in beverage testing, providing a clear background for ID.
- Aqueous Filtration - Biologically inert composition provides high flow rates and consistent reliability for routine laboratory fluid processing.
- Black Grid Analysis - Black membrane variants enhance contrast for light-colored colonies, reducing eye strain during manual plate counting.