ME25/21 ST 0.45um 50mm 100/Pk SKU: 10406872

Mixed Cellulose Ester (MCE) Membrane Filters - 10406872

The Whatman 10406872 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Equally important, a uniform Mixed Cellulose Ester (MCE) matrix maintains its rated 0.45 cutoff under the pressures and flow conditions encountered during routine laboratory filtration. In effect, precision manufacturing ensures that each membrane disc delivers the rated retention, flow rate, and surface consistency that analytical and microbiological methods require.

Material Specifications

• Single-unit sterile packaging maintains aseptic integrity through storage and handling, supporting cleanroom protocols and GMP-compliant workflows.
• Hydrophilic by nature, the MCE membrane structure supports high non-specific adsorption for effective organism capture.
• The biologically inert blend of cellulose acetate and cellulose nitrate provides a membrane surface optimized for organism capture and colony enumeration in microbiological assays.
• Known for excellent wetting properties and high flow rates in aqueous filtration.
• Feature a uniform pore structure that provides consistent flow rates and high throughputs across the full range of standard pore size ratings.

When your analytical method specifies membrane filtration as a sample preparation step, the retention characteristics and extractable profiles documented above allow you to meet method requirements without additional qualification work. MCE's naturally hydrophilic surface allows immediate wetting upon contact with aqueous samples, eliminating the pre-conditioning step and letting you begin filtration as soon as the membrane is seated in your holder. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

40.6psi

Color

white

Diameter

50mm

Extractables

low

Filtration Area

19.63cm²

Flow Rate

60ml (Water)

Grid (Yes/No)

Yes

Material

Mixed Cellulose Esters (MCE)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

130°C

Membrane Thickness (µm)

145um

Pack Count

100

pH Range

4-8

Pore Size (µm)

0.45

Sterility

Sterile

Sterilization

Supplied Sterile (Single Use)

Support Material

None

Wettability

Hydrophilic

• Yeast & Mold Monitoring - Optimized for the recovery of larger fungal organisms in beverage testing, providing a clear background for ID.
• Black Grid Analysis - Black membrane variants enhance contrast for light-colored colonies, reducing eye strain during manual plate counting.
• Microscopy mounting - Can be made transparent with immersion oil, allowing for direct light microscopy of retained particles on the surface.
• Water Quality Testing - Features a gridded surface for easy colony counting, essential for regulatory compliance in municipal water quality labs.
• Aqueous Filtration - Biologically inert composition provides high flow rates and consistent reliability for routine laboratory fluid processing.
• Bioburden Monitoring - Routine testing of pharmaceutical water loops to ensure bioburden levels remain within safe production specifications.