Nuclepore Hydrophilic Membrane, 10.0um Pore Size, 25mm Circle, 100/Pk SKU: 10418406

Polycarbonate Track-Etched (PCTE) Membrane Filters - 10418406

The Whatman 10418406 protects sensitive instrumentation and sample integrity by providing reliable particulate removal with minimal analyte adsorption or background interference. Moreover, verified 10.0 pore distribution across the Hydrophobic membrane surface guarantees batch-to-batch consistency in particle capture and analyte passage. In combination, controlled production conditions produce membranes with documented pore size distribution and thickness tolerances, supporting method reproducibility across multiple filter lots.

Material Specifications

• Track-etched Polycarbonate membranes feature perfectly cylindrical pores for absolute fractionation.
• Manufactured with tight pore size control for precise separation of cells and particulates.
• Optically clear construction enables direct on-membrane visualization of captured particles without transfer or additional preparation.
• Low protein binding and biologically inert surface properties make track-etched Polycarbonate compatible with cell biology and cytology workflows.
• Offer a smooth, flat glass-like surface specifically designed for microscopy analysis.

Maintaining accreditation under ISO 17025 or similar quality frameworks requires documented traceability at every step — the specification compliance of each membrane lot supports your ongoing audit readiness. Because track-etched pores are uniform in diameter across the entire membrane surface, the retention characteristics you validate during method development remain consistent from disc to disc — eliminating a variable in your quality-critical particle analyses. Secure your research outcomes by partnering with a filtration solution that understands your need for speed, accuracy, and reproducibility.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

N/A

Color

translucent

Diameter

25mm

Extractables

very low

Filtration Area

4.91cm²

Flow Rate

30 L (Air)

Grid (Yes/No)

No

Material

Polycarbonate (PC)

Maximum Operating Pressure

Holder-dependent

Maximum Operating Temperature (°C)

140°C

Membrane Thickness (µm)

6–11um

Pack Count

100

pH Range

2-11

Pore Size (µm)

10

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Support Material

None

Wettability

Hydrophobic

• Exosome Isolation - Separates extracellular vesicles from larger cell debris using defined pore sizes, preventing contamination in RNA analysis.
• Parasite Detection - Concentrates blood samples to detect microfilariae on a transparent surface, simplifying identification without staining.
• Liposome Sizing - Used in extrusion devices to force lipid suspensions through exact pores, creating uniform unilamellar vesicles for drug delivery.
• Erythrocyte Deformability - Mimics capillary dimensions to test red blood cell flexibility and rheology in clinical hemorheology research.
• Chemotaxis Migration - Acts as a precise barrier in Boyden chambers to measure cell migration towards chemoattractants without passive diffusion.
• Oceanographic Sampling - Fractionates plankton populations by size in seawater, ensuring precise separation for biomass and diversity studies.