Nylon Capsule Filter, 0.22 um, 72mm x 115mm, 1/4 in. MNPT, Nonsterile, 1/Pk SKU: SF14948

Nylon Capsule Filters - SF14948

The naturally hydrophilic structure of nylon capsule filters eliminates pre-wetting requirements, enabling immediate use with aqueous solutions while maintaining compatibility with most organic solvents. Built for consistent results, nylon membrane construction in the pleated capsule format delivers the effective filtration area needed for large-volume reagent preparation while maintaining the chemical versatility that defines this material. The result is a filtration process that eliminates cleaning validation, reduces changeover time, and provides batch-to-batch consistency through factory-tested, integrity-verified devices.

Key Nylon Membrane Characteristics

• Nylon capsule filters resist common laboratory solvents including alcohols, esters, and bases, while maintaining stable performance above pH 3 across typical processing conditions.
• Internal holdup volume of 60 milliliters minimizes sample loss during capsule filtration, a critical consideration when processing expensive biologics or limited-volume preparations.
• The mechanical strength of nylon membrane construction supports the operating pressures encountered in capsule filtration systems without the deformation risks associated with thinner membrane materials.
• The broad solvent compatibility of nylon membranes extends across aqueous, alcoholic, and many organic systems, providing a versatile capsule platform for laboratories processing diverse reagent types.
• Single-membrane construction simplifies integrity test interpretation, as the bubble point and diffusion flow values correspond directly to the rated retention membrane without prefilter interference.

Key Capsule Construction Features

• Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
• Thermally fused polypropylene construction eliminates adhesives, binders, and O-rings from the fluid path, reducing extractable contamination and simplifying material qualification.
• Polypropylene capsule housing supports autoclave sterilization at 121 degrees Celsius and withstands gamma irradiation exposure, accommodating both user-sterilized and factory-sterilized device configurations.
• Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.

From method development through scale-up to production, your capsule filter choice defines the balance between membrane performance, process integration, and the regulatory documentation trail that supports each filtration event. In this context, for facilities processing buffers, reagents, and mixed solvent systems, nylon capsule filters provide the chemical versatility your multi-application laboratory environment demands. Make the decision for consistency and reliability, ensuring that your laboratory maintains its reputation for high-quality, error-free output.

Sterilization Guidance

Non-sterile delivery accommodates applications where sterility is not required, while the all-polypropylene construction provides the option for autoclave sterilization when aseptic processing is specified.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

36.3psi

Compliance Standards

ISO 9001

Connection Type

1/4 in. MNPT

Construction

Polypropylene

Diameter

72mm

Dimensions

72mm x 115mm

Filling Bell (Yes/ No)

No

Filtration Area

1000cm²

Flow Rate

0.5 L/min at 0.1 bar

Holdup Volume

60mL

Inlet Connection

1/4 in. MNPT

Length

115mm

Material

Nylon

Max Batch Volume

＜50L

Maximum Operating Pressure

75.4psi

Maximum Operating Temperature (°C)

80°C

Outlet Connection

1/4 in. MNPT

Pack Count

1

Pore Size (µm)

0.22

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclavable at 121°C for 30 mins

Vent (Yes/ No)

Yes

Weight

0.39

Wettability

Hydrophilic

• Mixed Solvents - Filtration of aqueous-organic solvent mixtures without pre-wetting steps required by hydrophobic membrane alternatives.
• Aqueous Processing - Hydrophilic membrane filtration of water-based solutions with immediate wetting and full surface area utilization.
• Laboratory General - Versatile capsule filtration platform for multi-application laboratories processing diverse solution types at volume.
• Sample Clarification - Large-volume clarification of environmental, industrial, and laboratory samples prior to analytical testing.
• Environmental Samples - Processing of water, soil extract, and environmental samples requiring both particulate removal and volume capacity.
• Chemical Solutions - Filtration of alcohols, esters, and mild organic solvents compatible with the broad chemical tolerance of nylon membranes.