Tisch
Nylon Syringe Filters, Positive Charge, 0.22 um, 25mm, Sterile, 50/Pk SKU: SF02225NPS

Nylon Syringe Filters - SF02225NPS

The SF02225NPS nylon syringe filters feature a 25mm diameter with 0.22µm pore size and positive charge modification, providing enhanced sterile filtration and sterilization capabilities with superior retention of negatively charged particles and endotoxins. Tisch Scientific's positively charged syringe filters excel at removing bacteria while simultaneously binding endotoxins, DNA, and other negatively charged contaminants that standard filters might miss. SF02225NPS filters deliver dual-action purification through both size exclusion and electrostatic attraction, making them ideal for critical applications requiring the highest purity sterile filtrates.

Key Nylon Membrane Characteristics

• Positive charge surface modification actively binds negatively charged contaminants, including endotoxins, nucleic acids, and host cell proteins, through electrostatic interactions
• 0.22µm absolute pore rating ensures complete bacterial removal and sterilization, while the charged surface provides additional contaminant capture beyond size exclusion
• Naturally hydrophilic membrane enables immediate filtration without pre-wetting, maintaining consistent 1.34ml/min flow rates for efficient sample processing
• Pre-sterilized by radiation eliminates preparation steps and ensures contamination-free filtration with validated sterility assurance for critical applications
• Enhanced binding capacity captures trace contaminants that neutral membranes cannot retain, providing superior purification for sensitive biological applications

Key Construction Characteristics

• Medical-grade polypropylene housing provides exceptional chemical resistance and maintains structural integrity at operating pressures up to 87 psi
• 25mm diameter format offers 2.98cm² effective filtration area optimized for standard volume sterile filtration with enhanced contaminant removal
• Universal Luer-Lok/Luer Slip compatibility ensures aseptic connections with sterile syringes while preventing contamination during critical procedures
• Radiation-sterilized packaging maintains product sterility and charged membrane integrity without exposure to heat or moisture

SF02225NPS syringe filters provide the advanced purification your most critical applications demand through the combination of sterilizing filtration and positive charge technology. Tisch Scientific's dual-action filtration ensures you'll achieve not only bacterial removal but also reduction of endotoxins and other charged contaminants that compromise your results. Your sensitive biological applications benefit from the enhanced purity that makes the SF02225NPS essential when standard sterile filtration alone isn't sufficient for your quality requirements.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.98cm²

Flow Rate

1.34ml/ min @ 10psi.

Material

Nylon

Maximum Operating Pressure

6bar/ 87psi.

Pack Count

50

Pore Size (µm)

0.22

Sterility

Sterile

Sterilization

Radiation Sterilization

Wetability

Hydrophilic

• Endotoxin Reduction - Removal of bacterial endotoxins from protein solutions, cell culture media, and pharmaceutical preparations requiring low endotoxin levels
• Nucleic Acid Removal - Elimination of DNA and RNA contaminants from protein preparations, vaccines, and biological therapeutics
• Enhanced Cell Culture Sterilization - Sterile filtration of growth media with simultaneous removal of trace contaminants that affect sensitive cell lines
• Biopharmaceutical Processing - Production of high-purity injectable solutions and parenteral formulations requiring both sterility and contaminant reduction
• Protein Purification - Removal of host cell proteins and negatively charged aggregates from recombinant protein solutions
• Viral Vector Preparation - Sterilization and purification of gene therapy vectors requiring removal of process-related impurities