Tisch
Nylon Syringe Filters, Positive Charge, 0.45um, 25mm, Nonsterile, 100/Pk SKU: SF04525NP

Nylon Syringe Filters - SF04525NP

Featuring positively charged nylon membrane technology specifically engineered for endotoxin removal from water, buffers, and pharmaceutical process fluids. Nonsterile filters deliver effective clarification through 0.45µm pores while actively binding negatively charged contaminants. Advanced polypropylene construction ensures chemical stability and dimensional integrity throughout critical purification procedures.

Key Nylon Membrane Characteristics

• Positively charged surface actively binds and removes negatively charged endotoxins and pyrogens
• Naturally hydrophilic membrane requires no pre-wetting for immediate aqueous solution filtration
• Optimal 0.45µm pore size effectively removes particulates while maintaining excellent flow rates
• Moderate bubble point of 23.0psi confirms consistent pore distribution and membrane integrity
• Uniform 90-120µm membrane thickness provides reliable filtration performance across diverse samples
• Excellent chemical compatibility with aqueous non-acidic solutions and compatible organic solvents

Key Construction Characteristics

• Ultra-low holdup volume of 50µl minimizes sample loss and maximizes recovery efficiency
• Dual Luer-Lok inlet and Luer slip outlet connections provide secure attachment to standard syringes
• Robust polypropylene housing withstands 87psi operating pressure for consistent performance
• Compact 2.98cm² filtration area optimized for standard-volume endotoxin reduction applications

SF04525NP syringe filters provide the specialized endotoxin reduction your laboratory requires for contamination-sensitive analytical applications. Positively charged membrane technology combined with 0.45µm particle removal ensures your samples achieve both clarification and endotoxin reduction. Autoclavable or gamma-sterilizable design allows your team to prepare custom sterile clarification assemblies while maintaining workflow efficiency for pharmaceutical and critical manufacturing applications.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

23.0psi

Burst Pressure (psi)

87psi

Connection Type

Luer-Lok/Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.98cm²

Flow Rate

18.0ml

Holdup Volume

50ul

Material

Nylon

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

90-120µm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave: 121° C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

50ml

Weight

0.52

Wetability

Hydrophilic

• Endotoxin Reduction - Reduces bacterial endotoxin levels from water and buffers using positive charge adsorption mechanisms during clarification
• High-Purity Water Processing - Removes particulates and trace endotoxins from laboratory water to ensure purity for sensitive analytical testing
• Buffer Solution Clarification - Clarifies buffers while binding negatively charged pyrogens to protect sensitive downstream biological assays
• Pharmaceutical Process Water - Reduces endotoxin load in non-protein solutions to support strict pharmaceutical quality control standards
• Genomic Workflow Support - Clarifies wash buffers and reagents to minimize endotoxin interference in sensitive molecular biology protocols
• Vaccine Buffer Preparation - Reduces endotoxin levels in buffers and salts used in vaccine production to ensure strict regulatory compliance