Nylon Syringe Filters, Positive Charge, 0.45um, 25mm, Nonsterile, 100/Pk
Tisch SKU: SF04525NP

Tisch Scientific Nylon Syringe Filters, 0.45 µm, 25 mm, 100/Pk - SF04525NP

Tisch Scientific keeps ordering simple, turning quotes and questions around quickly. Sample preparation for chromatography often ends with a syringe filter on the path to the vial. Nylon delivers sharp particle cutoff at the rated pore size while shipping in economical bulk non-sterile packaging and resists alkaline buffer systems. The polypropylene housing contributes minimal extractables to the filtrate while staying inert across common laboratory solvents and maintains a low-dead-volume internal flow path. For routine sample preparation across many methods, the syringe filter folds clarification into one disposable step.

Technical Specifications

• Low extractable contribution to sensitive analytical preparations
• Naturally hydrophilic surface wets without pre-wetting in aqueous applications
• Broad compatibility with alcohols, aliphatic, and aromatic solvents
• Non-sterile for routine clarification and sample prep
• Absolute pore size rating provides consistent results across filtration protocols

Housing Specifications

• Medical-grade polypropylene with broad chemical compatibility
• Rigid polypropylene body holds its shape under manual filtration pressure
• Tough polypropylene body tolerates repeated handling at the bench
• Low extractable contribution protects sensitive downstream analyses

Filtering particulates upstream protects the column investment your methods depend on. Upstream buffer clarification keeps avoidable particulates out of your flow path while keeping the filtrate analytically clean. Call on the Tisch Scientific team to standardize filtration products across your methods with volume pricing and documentation.

For more information about chemical compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

23.0psi

Burst Pressure (psi)

87psi

Connection Type

Luer-Lok/Luer Slip

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

2.98cm²

Flow Rate

18.0ml

Holdup Volume

50ul

Material

Nylon

Maximum Operating Pressure

87psi

Maximum Operating Temperature (°C)

60°C

Membrane Thickness (µm)

90-120µm

Pack Count

100

Pore Size (µm)

0.45

Prefilter (Yes/No)

No

Sterility

Nonsterile

Sterilization

Autoclave: 121° C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput (ml)

50ml

Weight

0.52

Wettability

Hydrophilic

• Endotoxin Reduction - Reduces bacterial endotoxin levels from water and buffers using positive charge adsorption mechanisms during clarification
• High-Purity Water Processing - Removes particulates and trace endotoxins from laboratory water to ensure purity for sensitive analytical testing
• Buffer Solution Clarification - Clarifies buffers while binding negatively charged pyrogens to protect sensitive downstream biological assays
• Pharmaceutical Process Water - Reduces endotoxin load in non-protein solutions to support strict pharmaceutical quality control standards
• Genomic Workflow Support - Clarifies wash buffers and reagents to minimize endotoxin interference in sensitive molecular biology protocols
• Vaccine Buffer Preparation - Reduces endotoxin levels in buffers and salts used in vaccine production to ensure strict regulatory compliance