Tisch
Nylon Syringe Filters, 0.45um, 4mm, Luer-Lok/Luer Slip, Nonsterile, 200/Pk SKU: SF17503

Nylon Syringe Filters - SF17503

The SF17503 nylon syringe filters feature a 4mm diameter and 0.45µm pore size, providing specialized filtration for ultra-small volume applications where sample preservation is critical. These hydrophilic membrane filters excel at sample clarification and particulate removal in analytical preparations, delivering consistent performance for precious samples and microvolume analyses. The compact 4mm format minimizes holdup volume to just 5µl, making these filters ideal for applications where every microliter of sample matters.

Key Nylon Membrane Characteristics

• Broad chemical compatibility enables filtration of both aqueous and organic solvents, supporting diverse analytical workflows from HPLC sample preparation to biological assays
• Natural hydrophilicity eliminates the need for pre-wetting, allowing immediate filtration of aqueous solutions while maintaining consistent flow rates throughout processing
• 0.45µm pore size effectively removes particulates and cellular debris for sample clarification without removing dissolved proteins or small molecules
• Low protein binding characteristics preserve sample integrity during filtration, particularly important for dilute protein solutions and bioanalytical applications
• Temperature stability up to 100°C permits filtration of heated samples and supports autoclave sterilization at 121°C for 30 minutes when sterility is required

Key Construction Characteristics

• Polypropylene housing provides excellent chemical resistance and structural integrity at operating pressures up to 87 psi burst pressure
• Luer-Lok/Luer Slip compatibility ensures secure connections with standard syringes while preventing sample loss during filtration
• Minimal 5µl holdup volume maximizes sample recovery, critical for expensive reagents and limited-quantity biological samples
• 0.125cm² filtration area optimized for microvolume applications, providing controlled flow rates of 0.8ml/min at 10 psi

These specialized syringe filters deliver exceptional performance for ultra-low volume applications where sample conservation is paramount. The combination of nylon membrane chemistry and minimal holdup volume design ensures maximum sample recovery while maintaining the filtration quality essential for accurate analytical results. Researchers can confidently process their most valuable samples knowing that these filters provide the reliability and consistency required for reproducible experimental outcomes.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point

0.18psi.

Burst Pressure

87psi.

Connection Type

Luer-Lok/ Luer Slip

Construction

Polypropylene (PP)

Diameter

4mm

Filtration Area

0.125cm²

Flow Rate

0.8ml/ min @ 10psi.

Holdup Volume

5ml

Incompatibility

Acids, agressive organics, protein

Material

Nylon

Maximum Operating Temperature

100°C

Pack Count

200

Pore Size (µm)

0.45

Sterility

Nonsterile

Sterilization

Autoclave: 121°C for 30 minutes/ Gamma: 5kg, for 8 hours

Volume Throughput

1ml

Wetability

Hydrophilic

• Microvolume HPLC Sample Preparation - Clarification of injection samples to protect analytical columns from particulate contamination while preserving analyte concentrations
• Cell Culture Clarification - Removal of cellular debris from culture supernatants for downstream analysis of secreted proteins and metabolites
• Precious Sample Processing - Filtration of limited-quantity samples in proteomics and biomarker discovery where sample loss must be minimized
• Dissolution Testing - Clarification of dissolution media samples for pharmaceutical quality control testing and formulation development
• Environmental Sample Analysis - Preparation of water and soil extracts for trace analysis where sample volumes are restricted
• Enzyme Assay Preparation - Removal of particulates from enzyme solutions and substrates to ensure optical clarity in spectrophotometric measurements