Tisch
Nylon Syringe Filters, 0.22 um, 25mm, Double Luer Lock, PP Housing, Sterile, 100/Pk SKU: SPEC18121

Nylon Syringe Filters - SPEC18121

Featuring hydrophilic nylon membrane technology with 0.22µm pore size for sterile filtration and complete bacteria removal. Pre-sterilized filters deliver reliable performance for heat-sensitive biological samples, cell culture media, and pharmaceutical preparations requiring microbial control. Robust polypropylene housing combined with double Luer Lock connections ensures secure operation at pressures up to 72.5psi while maintaining chemical compatibility across aqueous and organic solvent applications.

Key Nylon Membrane Characteristics

• Naturally hydrophilic membrane allows immediate filtration of aqueous solutions without alcohol pre-wetting steps
• 0.22µm pore size provides absolute bacteria removal for sterile filtration of temperature-sensitive samples
• Broad chemical compatibility enables filtration of water, buffers, alcohols, DMSO, DMF, and laboratory solvents
• Moderate protein binding characteristics balance sample recovery with effective microbial retention capabilities
• Pre-sterilized packaging eliminates preparation steps for immediate use in aseptic techniques and clean environments

Key Construction Characteristics

• Polypropylene housing delivers superior chemical resistance while withstanding temperatures up to 80°C
• Double Luer Lock configuration with female inlet and male outlet prevents disconnection during pressurized operations
• Minimal holdup volume (<150µl typical for 25mm diameter) maximizes recovery of expensive or limited samples
• 4.9cm² effective filtration area provides optimal flow rates for efficient processing of standard laboratory volumes

SPEC18121 filters enhance your sterile filtration workflows with consistent 45psi bubble point performance, ensuring pore size integrity. Pre-sterilized packaging saves your laboratory preparation time while the 116psi burst pressure provides substantial safety margin for confident operation. Your sensitive samples benefit from the 25mm format's ideal balance between processing speed and filtration efficiency.

For more information about chemical and material compatibility, please review our Chemical Compatibility Chart.

Bubble Point (psi)

45psi

Burst Pressure (psi)

116psi

Connection Type

Double Luer Lock

Construction

Polypropylene (PP)

Diameter

25mm

Filtration Area

4.9cm²

Material

Nylon

Maximum Operating Pressure

72.5psi

Maximum Operating Temperature (°C)

80℃

Pack Count

100

Pore Size (µm)

0.22

Sterility

Sterile

Wetability

Hydrophilic

• Sterile filtration of cell culture media - Ensures bacteria-free growth conditions for mammalian cell line maintenance
• Heat-sensitive protein solutions - Preserves biological activity while achieving sterility without autoclave exposure
• HPLC sample preparation - Removes bacteria and particles protecting columns while maintaining analyte integrity
• Pharmaceutical formulation testing - Provides sterile filtration for drug stability studies and quality control
• Environmental water sterilization - Eliminates bacterial contamination for microbiological analysis and testing
• Buffer and reagent sterilization - Alternative to autoclaving for solutions containing heat-labile components