PTFE Capsule Filters - 12082
From HPLC mobile phase preparation to process gas venting, PTFE capsule filters handle the chemically aggressive applications where other membrane materials degrade or fail. The chemically inert PTFE membrane within the capsule housing resists degradation by virtually all organic solvents, strong acids, and alkaline solutions, enabling filtration of the most aggressive process fluids. The outcome is simplified regulatory documentation and reduced contamination risk, with each single-use capsule providing a validated, traceable filtration event.
Key PTFE Membrane Characteristics
- PTFE membrane chemistry withstands autoclave temperatures, supporting sterilization protocols where both the membrane and housing construction are rated for steam exposure.
- Non-sterile capsules support autoclave sterilization where the membrane and housing materials permit, allowing users to prepare devices according to their own validated sterilization protocols.
- PTFE capsule filters maintain mechanical integrity and retention performance at temperatures exceeding those tolerated by PES, PVDF, or nylon membranes, supporting high-temperature process filtration.
- Without an integrated prefilter, the full effective filtration area is dedicated to final retention, maximizing the available membrane surface for applications with clean or pre-filtered feed solutions.
- PTFE membrane capsules resist degradation by virtually all organic solvents, strong acids, bases, and oxidizing agents, providing universal chemical compatibility for aggressive filtration applications.
Key Capsule Construction Features
- Polypropylene housing materials provide documented biocompatibility and low extractable profiles, supporting integration into pharmaceutical and food-processing filtration applications.
- Single-use polypropylene capsule construction eliminates cleaning validation requirements, reducing the regulatory burden and turnaround time associated with reusable stainless steel filter housings.
- Barbed inlet and outlet connections provide a practical, leak-resistant interface for gravity-feed, peristaltic pump, and pressure-driven filtration systems using flexible tubing.
- Polypropylene capsule housing provides broad chemical compatibility from pH 1 to 14, resisting the acids, bases, and process chemicals that degrade alternative housing materials.
From method development through scale-up to production, your capsule filter choice defines the balance between membrane performance, process integration, and the regulatory documentation trail that supports each filtration event. In this context, if your workflow involves organic solvents, aggressive reagents, or process gas streams, the universal chemical resistance of PTFE membrane construction handles the harshest conditions your application presents. Elevate the quality of your analytical data today by standardizing on a filtration product built to meet the exact specifications of your applications.
Sterilization Guidance
Polypropylene construction throughout the device permits autoclave sterilization at standard conditions, enabling end-user preparation for sterile filtration applications as needed.
For more information about chemical compatibility, please review our Chemical Compatibility Chart.
- Bubble Point (psi)
- 18 psi
- Burst Pressure (psi)
- 60 psi
- Capsule Format
- AcroPak 300
- Compliance Standards
- USP Class VI <88>; Endotoxin < 0.25 EU/mL (LAL)
- Construction
- Polypropylene
- Diameter
- 6.7 cm
- Filling Bell (Yes/ No)
- No
- Filtration Area
- 280 cm²
- Flow Rate
- Water - 0.8 L; Air 32 L
- Inlet Connection
- Stepped hose barb
- Length
- 10.5 cm
- Material
- PTFE
- Max Batch Volume
- Medium-volume batch processing
- Maximum Operating Pressure
- 60 psi
- Maximum Operating Temperature (°C)
- 60 °C
- Membrane Brand
- Versapor
- Outlet Connection
- Stepped hose barb
- Pack Count
- 3
- Pore Size (µm)
- 0.2
- Prefilter (Yes/No)
- No
- Sterility
- Nonsterile
- Sterilization
- Autoclave
- Vent (Yes/ No)
- Yes
- Wettability
- Hydrophobic
- Solvent Filtration - Chemical-resistant filtration of HPLC mobile phases, aggressive organic solvents, and corrosive reagent solutions.
- Solvent Recovery - Clarification of recycled organic solvents to remove particulates accumulated during previous processing operations.
- HPLC Preparation - Particle removal from organic and mixed mobile phases prior to high-performance liquid chromatography analysis.
- Vent Protection - Membrane barrier filtration for fermentation vessel exhaust and bioreactor off-gas systems in bioprocessing facilities.
- Air Filtration - Point-of-use filtration of compressed air and nitrogen gas streams supplying clean manufacturing environments.
- Chemical Processing - Filtration of strong acids, bases, and aggressive organic chemicals that degrade PES, PVDF, and nylon membranes.